Results 1 to 10 of about 216,525 (294)

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Relation of Structure, Composition and Glass Forming Ability in Zr-Cu Binary Amorphous Alloys

MATEC Web of Conferences, 2016
Molecular dynamics simulation was used to simulate Zr-Cu binary system, in which the relationship between structure, composition and glass forming ability was study.
Dang Yizong, Wang Lu, Fan Qunbo
doaj   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

CALPHAD-enabled design of metallic glasses with target properties: Gold-based glass for jewellery

Materials & Design
The compositions of current metallic glasses are designed to ensure glass formation, and they can be far from optimal for intended applications. The composition changes needed to improve specific properties can lead to a loss of glass-forming ability ...
Owain S. Houghton, Yurii P. Ivanov, Nikolaos T. Panagiotopoulos, A. Lindsay Greer   +3 more
doaj   +1 more source

Role of bioglass derivatives in tissue regeneration and repair: A review

Reviews on Advanced Materials Science, 2023
Bioceramics are significantly contributing in repairing and reconstructing the defective areas of the musculoskeletal system. Bioactive glass is a non-crystalline bioceramic that has been widely used in regeneration due to its extensive bone-forming ...
Gao Yang, Seles Mohan Anne, Rajan Mariappan   +2 more
doaj   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

Glass forming ability, thermal stability and elastic properties of Zr-Ti-Cu-Be-(Fe) bulk metallic glasses

Results in Physics, 2016
A series of Zr35−xTi30Cu7.5Be27.5Fex (x = 0–10) bulk metallic glasses are cast using water-cooled copper mold casting technique. The glass forming ability (GFA) and thermal stability of Zr35−xTi30Cu7.5Be27.5Fex alloys were studied by means of X-ray ...
Haitao Zong, Linyan Bian, Jingyun Cheng, Guohua Cao, Chaoyang Kang, Ming Li   +5 more
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz, Christopher H. Thompson, Linda C. Laux, Alfred L. George Jr.   +3 more
wiley   +1 more source

Characterization of Surface Properties, Osteoblast Cell Culture in Vitro and Processing with Flow-Viscosity of Ni-Free Ti-Based Bulk Metallic Glass for Biomaterials

Journal of Biomechanical Science and Engineering, 2009
Ni-free type Ti-based metallic glass evaluated in this study has imposing performances for biomaterials that is based on high bulk forming ability (BFA) for implantable materials, superior specific strength, low Young's modulus as hard tissue ...
Jeong-Jung OAK, Gi-Wook HWANG, Yong-Ha PARK, Hisamichi KIMURA, Seog-Young YOON, Akihisa INOUE   +5 more
doaj   +1 more source