Results 61 to 70 of about 2,121,700 (294)
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
First result of large size Scintillating Glass GEM imager
EPJ Web of Conferences, 2018 A large size x-ray imaging gaseous detector, which has 280 × 280 mm2 effective area has been successfully developed and x-ray imaging has been demonstrated.
Fujiwara Takeshi +3 more
doaj +1 more source
On the existence of a finite-temperature transition in the two-dimensional gauge glass
, 2003 Results from Monte Carlo simulations of the two-dimensional gauge glass supporting a zero-temperature transition are presented. A finite-size scaling analysis of the correlation length shows that the system does not exhibit spin-glass order at finite ...
B.J. Kim +25 more
core +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Unusually thick shear-softening surface of micrometer-size metallic glasses
The Innovation, 2021 Summary: The surface of glass is crucial for understanding many fundamental processes in glassy solids. A common notion is that a glass surface is a thin layer with liquid-like atomic dynamics and a thickness of a few tens of nanometers.
J. Dong +7 more
doaj +1 more source
Direct experimental evidence of a growing length scale accompanying the glass transition
, 2005 Understanding glass formation is a challenge because the existence of a true glass state, distinct from liquid and solid, remains elusive: Glasses are liquids that have become too viscous to flow.
Berthier, Ludovic +7 more
core +3 more sources
Finite-size critical scaling in Ising spin glasses in the mean-field regime [PDF]
, 2016 We study in Ising spin glasses the finite-size effects near the spin-glass transition in zero field and at the de Almeida-Thouless transition in a field by Monte Carlo methods and by analytical approximations.
Aspelmeier, T. +5 more
core +3 more sources
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Lack of Ultrametricity in the Low-Temperature phase of 3D Ising Spin Glasses
, 2004 We study the low-temperature spin-glass phases of the Sherrington-Kirkpatrick (SK) model and of the 3-dimensional short range Ising spin glass (3dISG). For the SK model, evidence for ultrametricity becomes clearer as the system size increases, while for ...
A. P. Young +7 more
core +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source