Results 71 to 80 of about 8,722,473 (339)

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Melt pool size of optical glass irradiated by semiconductor laser

open access: yesJournal of Asian Ceramic Societies, 2023
Using a continuous laser to soften glass locally is a novel way of selective glass forming. Due to gaussian distribution of laser power density, a temperature gradient will be generated on glass treated with localized irradiation by laser, which brings ...
Weijie Fu   +3 more
doaj   +1 more source

Critical behavior of the three- and ten-state short-range Potts glass: A Monte Carlo study

open access: yes, 2006
We study the critical behavior of the short-range p-state Potts spin glass in three and four dimensions using Monte Carlo simulations. In three dimensions, for p = 3, a finite-size scaling analysis of the correlation length shows clear evidence of a ...
Katzgraber, Helmut G.   +2 more
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Unusually thick shear-softening surface of micrometer-size metallic glasses

open access: yesThe Innovation, 2021
Summary: The surface of glass is crucial for understanding many fundamental processes in glassy solids. A common notion is that a glass surface is a thin layer with liquid-like atomic dynamics and a thickness of a few tens of nanometers.
J. Dong   +7 more
doaj   +1 more source

Structure and dynamics of a model glass: influence of long-range forces

open access: yes, 2000
We vary the amplitude of the long-range Coulomb forces within a classical potential describing a model silica glass and study the consequences on the structure and dynamics of the glass, via molecular dynamics simulations.
Elliott S R   +10 more
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Controlled formation of gold nanoparticles with tunable plasmonic properties in tellurite glass

open access: yesLight: Science & Applications, 2023
Silicate glasses with metallic nanoparticles (NPs) have been of intense interest in art, science and technology as the plasmonic properties of these NPs equip glass with light modulation capability.
Yunle Wei   +5 more
doaj   +1 more source

Direct experimental evidence of a growing length scale accompanying the glass transition

open access: yes, 2005
Understanding glass formation is a challenge because the existence of a true glass state, distinct from liquid and solid, remains elusive: Glasses are liquids that have become too viscous to flow.
Berthier, Ludovic   +7 more
core   +3 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

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