Results 31 to 40 of about 27,499 (260)

Electrochemical detection of cefiderocol for therapeutic drug monitoring

Electrochemistry Communications, 2021
Cefiderocol is a novel siderophore-conjugated β-lactam antibiotic which has been approved for clinical use. It has demonstrated efficacy against infections caused by Gram-negative bacteria, including carbapenem-resistant strains.
James McLeod, Ellen Stadler, Richard Wilson, Alison Holmes, Danny O'Hare   +4 more
doaj   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

A Comparison of the Electrochemical Behavior of Rutin at an Inactivated, Activated, and Multi Wall Carbon Nanotubes Modified Glassy Carbon Electrode

International Journal of Electrochemical Science, 2009
Electrochemical characteristics of rutin, as an important biological molecule, have been studied at a glassy carbon electrode using cyclic voltammetry and chronocoulometry methods.
Hamid R. Zare, Reza Samimi, M. Mazloum Ardakani   +2 more
doaj   +1 more source

Electrochemical Deposition of Al-Ti Alloys from Equimolar AlCl₃ + NaCl Containing Electrochemically Dissolved Titanium

Metals, 2020
Al-Ti alloys were electrodeposited from equimolar chloroaluminate molten salts containing up to 0.1 M of titanium ions, which were added to the electrolyte by potentiostatic dissolution of metallic Ti.
Vesna S. Cvetković, Nataša M. Vukićević, Ksenija Milićević-Neumann, Srećko Stopić, Bernd Friedrich, Jovan N. Jovićević   +5 more
doaj   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Properties of Aluminium-Ceramic Composite with Glassy Carbon as Solid Lubricant Designed for Automotive Applications / Właściwości Kompozytu Aluminiowo Ceramicznego Zawierajacego Węgiel Szklisty Jako Smar Stały Przeznaczonego Dla Motoryzacji

Archives of Metallurgy and Materials, 2015
The paper presents some basic information on manufacturing, structure and selected properties of a new hybrid composite with an aluminium alloy matrix elaborated for automotive applications. A porous oxide ceramics constitute the reinforcing phase of the
Posmyk A., Myalski J., Wistuba H.
doaj   +1 more source

Role of sp2 carbon in non-enzymatic electrochemical sensing of glucose using boron-doped diamond electrodes

Electrochemistry Communications, 2021
Boron-doped diamond (BDD) is of increasing interest for applications in electrochemical sensing. It is well known that the sp2 carbon content in BDD influences its electrochemical properties as electrode material.
Zhichao Liu, André F. Sartori, Josephus G. Buijnsters   +2 more
doaj   +1 more source

Glassy carbon paste electrodes

Electrochemistry Communications, 2001
A new carbon composite electrode material, based on mixing glassy carbon (GC) microparticles with an organic pasting liquid is described. The resulting glassy carbon paste electrode (GCPE) combines the electrochemical properties of GC with the various advantages of composite electrodes. Glassy carbon pastes (GCPs) offer high electrochemical reactivity,
Joseph Wang, Ülkü Anik Kirgöz, Jian-Wei Mo, Jianmin Lu, Abdel Nasser Kawde, Alexandr Muck   +5 more
openaire   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Voltammetric determination of nicotine in cigarette tobacco at electrochemically activated glassy carbon electrode

Bulletin of the Chemical Society of Ethiopia, 2013
The electrochemical behavior of nicotine was investigated using cyclic and square wave voltammetric techniques. Electrochemical activation of glassy carbon electrode significantly increased the oxidation peak current of nicotine compared to the bare ...
A. Geto, S. Admassie, H. Kassa
doaj   +1 more source