Results 91 to 100 of about 70,105 (255)

Protein misfolding and mitochondrial dysfunction in glaucoma

Frontiers in Cell and Developmental Biology
Glaucoma is a leading cause of irreversible blindness worldwide. Elevated intraocular pressure caused by restricted outflow of the aqueous humor leads to the degeneration of retinal ganglion cells (RGCs) and their axons.
Arunkumar Venkatesan, Audrey M. Bernstein, Audrey M. Bernstein   +2 more
doaj   +1 more source

Risk of open angle glaucoma due to tumor necrosis factor alpha gene polymorphisms

Electronic Physician, 2016
Introduction: Axonal degeneration and retinal ganglion cell apoptosis in glaucoma is associated with tumor necrosis factor alpha (TNF-α), which is an important pro-inflammatory cytokine.
Mona Abdel Hamid, Leqaa Moemen, Hany Labib, Hazem Helmy, Tarek Elsergany   +4 more
doaj   +1 more source

Adult‐onset Coats disease: A systematic review and meta‐analysis of imaging biomarkers and targeted therapies

Acta Ophthalmologica, EarlyView.
Abstract Coats disease diagnosed in adulthood is a rare idiopathic retinal telangiectatic vasculopathy that may differ in phenotype from childhood‐diagnosed cases. This systematic review synthesizes current evidence to characterize its clinical spectrum, imaging features, treatment outcomes and underlying mechanisms, with a focus on immunovascular ...
Catarina Francisco, Nisa Silva, Camiel J. F. Boon   +2 more
wiley   +1 more source

Real‐world insights on switching aflibercept dosage for enhanced outcomes in age‐related macular degeneration (RISE‐AMD): Safety data

Acta Ophthalmologica, EarlyView.
Abstract Purpose To evaluate real‐world safety experience with aflibercept 8 mg in a large case series of patients with neovascular age‐related macular degeneration (nAMD). Methods Due to a high proportion of patients on short treatment intervals, patients with nAMD at a Danish tertiary retina clinic were systematically switched to aflibercept 8 mg ...
Mary Graciya Karunainathan, Celine Lee, Kaweh Daniel Zohalinejad, Mads Odgaard Mæng, Nanna Würtz Fabrin, Sigurrós Jónsdóttir, Anne Kjærsgaard Hassing, Søren Kveiborg Yde, Charles C. Wykoff, Henrik Vorum, Yousif Subhi, Marie Ørskov, Lasse Jørgensen Cehofski   +12 more
wiley   +1 more source

The role of the local and general somatic factors for the open-angle glaucoma development in patients with eye manifestations of pseudoexfoliation syndrome

Офтальмохирургия, 2013
Pseudoexfoliation syndrome (PEX) is one of the best known triggers of glaucoma. The development of the open-angle glaucoma only in some patients with the PEX with definite local and general risk factors requires a further research. Purpose.
V.V. Agafonova,, M.Z. Frankovska-Gerlak, T.V. Sokolovskaya, P.E. Brizhak,, A.N. Bessarabov   +4 more
doaj  

Open Angle Glaucoma and Stroke [PDF]

Ophthalmology, 2010
Dustin D, French, Curtis E, Margo
openaire   +2 more sources

Real‐world incidence and clinical characteristics of intraocular inflammation following intravitreal faricimab therapy: A safety study

Acta Ophthalmologica, EarlyView.
Abstract Purpose To estimate the real‐world incidence of intraocular inflammation (IOI) following intravitreal faricimab injections at a large, highly specialized tertiary centre. Methods Single‐centre, retrospective cohort study with chart review using an electronic injection database and electronic medical records from November 2023 to August 2024 ...
Miklos Schneider, Leyla Turan, Farah Arif, Jakob Bjerager, Oliver Niels Klefter, Carsten Faber, Yousif Subhi, Javad Nouri Hajari   +7 more
wiley   +1 more source

Epidemiological characterization of primary open-angle glaucoma

Medisur, 2010
Background: The primary open-angle glaucoma is a problem for public health all over the world. It is a silent and slowly progressive disease leading to blindness.
Leonor Rosario Díaz Alfonso, Bárbara Nuria Suárez Rodríguez, Mariela Julia Curbelo, Yusdenia Soto Serrano, Armando Rafael Milanés Armengol   +4 more
doaj   +2 more sources

Variation in measuring and ophthalmic factors correlating with central corneal thickness in the Northern Finland birth cohort eye study

Acta Ophthalmologica, EarlyView.
Abstract Purpose To assess the correlation between optical coherence tomography (OCT) and ultrasound pachymetry (USP) as methods for analysing central corneal thickness (CCT) and to evaluate ophthalmic factors affecting CCT. Methods The eyes of 3070 subjects of the Northern Finland Birth Cohort (NFBC) were examined at the age of 45–49 years.
Tuomas Qvist, Oona Ahokas, Johanna Liinamaa, Ville Saarela   +3 more
wiley   +1 more source

Corneal Biomechanics for Ocular Hypertension, Primary Open-Angle Glaucoma, and Amyloidotic Glaucoma: A Comparative Study by Corvis ST

Clinical Ophthalmology, 2022
Nisa Silva,1 André Ferreira,1,2 Pedro Manuel Baptista,1 Ana Figueiredo,1 Rita Reis,1 Isabel Sampaio,1 João Beirão,1,3 Riccardo Vinciguerra,4,5 Pedro Menéres,1,3 Maria João Menéres1,3 1Ophthalmology Department, Centro Hospitalar Universitário do Porto ...
Silva N, Ferreira A, Baptista PM, Figueiredo A, Reis R, Sampaio I, Beirão J, Vinciguerra R, Menéres P, Menéres MJ   +9 more
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