Results 161 to 170 of about 112,057 (268)

Ibudilast Protects Retinal Bipolar Cells From Excitotoxic Retinal Damage and Activates the mTOR Pathway

Glia, Volume 73, Issue 5, Page 905-927, May 2025.
Main Points Ibudilast, a MIF and PDE inhibitor, preserves the form and function of the retina, especially bipolar cells, during excitotoxic damage. Ibudilast upregulates multiple signaling pathways, including mTOR, in damaged Müller glia and bipolar cells.
Sumaya Hamadmad, Tyler Heisler‐Taylor, Sandeep Goswami, Evan Hawthorn, Sameer Chaurasia, Dena Martini, Diana Summitt, Ali Zatari, Rahaf Shalash, Misha Sohail, Elizabeth G. Urbanski, Kayla Bernstein, Julie Racine, Abhay Satoskar, Heithem M. El‐Hodiri, Andy J. Fischer, Colleen M. Cebulla   +16 more
wiley   +1 more source

Dysregulation of Astrocytic ATP/Adenosine Release in the Hippocampus Cause Cognitive and Affective Disorders: Molecular Mechanisms, Diagnosis, and Therapy

MedComm, Volume 6, Issue 5, May 2025.
Reactive astrocytes release various molecules, which play a role in maintaining central nervous system (CNS) homeostasis. (1) Gliotransmitters, such as glutamate, γ‐aminobutyric acid (GABA), ATP, and D‐serine, are secreted by vesicular exocytosis. In addition, astrocytes can also release ATP and glutamate through (2) P2X7Rs, (3) connexin‐43 (Cx43 ...
Peter Illes, Patrizia Rubini, Henning Ulrich, Hai‐Yan Yin, Yong Tang   +4 more
wiley   +1 more source

Primary open-angle glaucoma: everyone’s business

Community Eye Health Journal, 2012
Primary open-angle glaucoma (POAG) is sometimes called the ‘thief of sight’. There is no pain or discomfort, and vision loss is so gradual that people often do not notice it.POAG cannot be cured: it requires ongoing treatment for the remainder of a ...
Hannah Faal
doaj  

Central Nervous System Depression After Topical Administration of Brimonidine Eye Drops to Induce Vomiting in a Cat

Veterinary Medicine and Science, Volume 11, Issue 3, May 2025.
A 12‐year‐old neutered male American Shorthair cat was presented to the hospital after ingesting toxic plants to cats. Brimonidine instillation was performed to induce vomiting. Three incidents of projectile vomiting were then observed 30 min after the brimonidine administration.
Dalhae Kim, Jaehan Jun, Eunbin Park, Joohyun Jung, Won‐gyun Son   +4 more
wiley   +1 more source

Evaluation of a New Non‐Mydriatic Handheld Fundus Camera for Fundus Imaging in Cats: A Retrospective Study: 208 Cases (2023–2024)

Veterinary Medicine and Science, Volume 11, Issue 3, May 2025.
A non‐mydriatic handheld fundus camera (Aurora, Optomed, Oulu, Finland) was evaluated for feline fundus imaging, providing high‐quality images without pupil dilation. The device demonstrated excellent centration, clarity and visibility in 416 eyes, making it a practical and less stressful alternative for veterinary ophthalmic examinations .
Özlem Şengöz Şirin, Mehmet Nur Çetin, Muhammed Yusuf Şirin   +2 more
wiley   +1 more source

Vitrectomy in Small idiopathic MAcuLar hoLe (SMALL) study: Internal limiting membrane peeling versus no peeling

Acta Ophthalmologica, Volume 103, Issue 3, Page e156-e164, May 2025.
Abstract Purpose To compare vitrectomy with and without internal limiting membrane (ILM) peeling in small idiopathic macular holes. Methods Retrospective multicentre study including consecutive eyes with ≤250 μm idiopathic macular hole treated with vitrectomy. The primary outcome was hole closure rate.
Paola Marolo, Paolo Caselgrandi, Matteo Fallico, Guglielmo Parisi, Enrico Borrelli, Federico Ricardi, Francesco Gelormini, Luca Ceroni, Michele Reibaldi, SMALL Study Group, Tommaso Micelli Ferrari, Massimo Lorusso, Vito Primavera, Gianluigi Giuliani, Cesare Mariotti, Marco Lupidi, Luca Ventre, Giulia Pintore, Lorenzo Motta, Matteo Ripa, Francesco Boscia, Giacomo Boscia, Mario R Romano, Mariantonia Ferrara, Kacerik Miroslav, Daniele Marchina, Barbara Parolini, Enrico Peiretti, Viola Marchiori, Roberto Dell’Omo, Marzia Affatato, Teresio Avitabile, Andrea Russo, Antonio Longo, Vincenzo Scorcia, Adriano Carnevali, Rodolfo Mastropasqua, Lisa Toto, Agostino Salvatore Vaiano, Riccardo Merli, Marco Mura, Marco Pellegrini, Fabrizio Giansanti, Cristina Nicolosi, Matteo Badino, Nicola Pallozzi Lavorante, Maria T. Sandinha, Francesco Maria D’Alterio, Mario Damiano Toro, Robert Rejdak, Paolo Chelazzi, Claudia Azzolini, Francesco Viola, Caterina Donà, Matteo Giuseppe Cereda, Marco Casaluci, Marco Codenotti, Lorenzo Iuliano, Grazia Pertile, Daniele Sindaco, Stefano De Cillà, Andrea Muraca, Vincenza M.E. Bonfiglio, Maria Vadalà, Alberto La Mantia, Viviana Randazzo, Tito Fiore, Gianluigi Tosi, Rino Frisina, Chiara Angeli, Marco Coassin, Mariateresa Laborante, Tommaso Rossi, Pamela Cosimi, Stanislao Rizzo, Matteo Mario Carlà, Magda Gharbiya, Giuseppe Maria Albanese, Luigi Caretti, Edoardo Angelini, Gian Marco Tosi, Tommaso Bacci, David H Steel, Nikolaos Dervenis, Iordanis Vagiakis, Daniele Tognetto, Marco Rocco Pastore, Francesco Faraldi, Carlo Alessandro Lavia, Paolo Lanzetta, Daniele Veritti, Leopoldo Rubinato, Paolo Radice, Andrea Govetto   +93 more
wiley   +1 more source

Higher risk and earlier onset glaucoma in Cushing's syndrome

Acta Ophthalmologica, Volume 103, Issue 3, Page e176-e182, May 2025.
Abstract Purpose Glaucoma incidence in patients with endogenous Cushing's syndrome (CS) has never been established. We aim to assess the risk for glaucoma among CS patients compared to controls and determine the age of disease onset. Methods A nationwide retrospective matched‐cohort study of patients with endogenous CS diagnosed between 2000 and 2023 ...
Yael Sharon, Tzipora Shochat, Yaron Rudman, Shiri Kushnir, Alon Zahavi, Ilan Shimon, Maria Fleseriu, Amit Akirov   +7 more
wiley   +1 more source

Long-Term Surgical Outcome of Trabeculectomy with Mitomycin C: A Comparison Between Primary and Secondary Glaucoma in Thailand. [PDF]

Clin Ophthalmol
Arampinyokul P, Rojananuangnit K.
europepmc   +1 more source

The ever ongoing cosmetic quest to change eye colour

Acta Ophthalmologica, Volume 103, Issue 3, Page 357-362, May 2025.
Abstract Purpose To provide a historical overview of the various efforts to change eye colour for purely cosmetic reasons, along with the associated potential risks and harms. Methods Literature and online search. Results Eye drops containing adrenaline were used during World War II on involuntary inmates of concentration camp Auschwitz‐Birkenau ...
Richard H. C. Zegers
wiley   +1 more source

Glaucoma prevalence and treatment in sub-Saharan Africa's elderly population: a scoping review. [PDF]

BMC Geriatr
Sarfo JO, Mordi P, Aggrey EK, Quaicoe ASP, Attafuah PYA.   +4 more
europepmc   +1 more source