Results 121 to 130 of about 464,611 (330)

Nanoparticle Therapeutics in Clinical Perspective: Classification, Marketed Products, and Regulatory Landscape

open access: yesSmall, EarlyView.
This review presents a detailed overview of clinically approved nanoparticle therapeutics, classifying them by type and discussing their unique advantages in drug delivery. It highlights regulatory challenges across global markets and emphasizes the need for adaptive approval pathways.
Nimeet Desai   +5 more
wiley   +1 more source

An Interpretable Artificial Intelligence System for Crohn's Disease Ulcer Identification and Grading on Double‐Balloon Enteroscopy Images

open access: yesUnited European Gastroenterology Journal, EarlyView.
ABSTRACT Background Crohn's disease (CD) is an incurable inflammatory bowel disease that can lead to a variety of complications and requires lifelong treatment. However, the diagnosis and management of Crohn's disease exhibit high rates of misdiagnosis and missed diagnoses, along with significant variability, among primary care facilities and novice ...
Qiuyuan Liu   +16 more
wiley   +1 more source

Comparison of the effects of an endotracheal tube and a V‐gel airway device on intraocular pressure and haemodynamic responses in anaesthetised cats

open access: yesVeterinary Record, EarlyView.
Abstract Background This study aimed to compare the effects of placing an endotracheal tube (ETT) versus a V‐gel airway device on intraocular pressure (IOP), heart rate (HR), mean arterial pressure (MAP) and peripheral oxygen saturation (SpO2) in anaesthetised cats.
Mehmet Nur Cetin   +5 more
wiley   +1 more source

The device that will be most useful to assess the angles in the next 10 years will be…

open access: yesPhilippine Journal of Ophthalmology, 2019

Edgar U. Leuenberger, MD   +2 more
doaj  

Correlation of optic nerve hemoglobin levels with structural and functional parameters in glaucoma

open access: yesScientific Reports
Glaucoma is a chronic and progressive eye disease that leads to irreversible damage to the optic nerve and retinal nerve fiber layer, resulting in visual field loss.
Gustavo Coelho Caiado   +6 more
doaj   +1 more source

Harmonizing NAD+ metabolism with CeMOF nanozyme to orchestrate intraocular pressure modulation for glaucoma treatment

open access: yesVIEW, EarlyView.
Our findings demonstrate that NAD+ metabolism dysregulation contributes to elevated intraocular pressure in glaucoma. Supplementation with NAD+ precursors reduces IOP by alleviating oxidative stress, cellular senescence, and extracellular matrix deposition.
Youjia Zhang   +10 more
wiley   +1 more source

Sustained intraocular pressure-lowering effect and biocompatibility of a single subconjunctival administration of hydrogel-encapsulated nano-brinzolamide

open access: yesJournal of Materials Science: Materials in Medicine
Brinzolamide is a widely used treatment for glaucoma, but its effectiveness relies on at least twice-daily dosing, which can be challenging for patient adherence.
Jiahao Xu   +6 more
doaj   +1 more source

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