Results 261 to 270 of about 324,734 (337)

The Landscape of SPP1+ Macrophages Across Tissues and Diseases: A Comprehensive Review

open access: yesImmunology, EarlyView.
SPP1+ macrophages represent a conserved, disease‐associated population present across cancerous and non‐cancerous conditions, involved in immunosuppression, fibrosis, lipid metabolism, phagocytosis, and other cellular processes. This review highlights their shared molecular programmes across tissues, their interactions with stromal and immune cells ...
Alessandro Palma
wiley   +1 more source

Reference genes validation in tear fluid for RNA analysis in ocular surface disease. [PDF]

open access: yesSci Rep
Ojeda DA   +7 more
europepmc   +1 more source

PIK3R1 mutations in individuals with insulin resistance or growth retardation: Case series and in silico functional analysis

open access: yesJournal of Diabetes Investigation, EarlyView.
We present a report on SHORT syndrome caused by PIK3R1 mutations, including findings from in silico analysis. Our results demonstrate that these mutations impair the ability of p85α to interact with phosphopeptides. ABSTRACT Aims/Introduction Phosphatidylinositol 3‐kinase (PI3K) plays a key role in insulin signaling, and mutations in PIK3R1, which ...
Tomofumi Takayoshi   +15 more
wiley   +1 more source

A case of SHORT syndrome with a novel genetic mutation diagnosed 19 years after the onset of diabetes

open access: yesJournal of Diabetes Investigation, EarlyView.
We report a case of SHORT syndrome caused by a novel PIK3R1 mutation. The diagnosis of SHORT syndrome was made based on typical clinical features suggestive of the syndrome. ABSTRACT A 33‐year‐old man presented with short stature, thin build, hearing impairment, Rieger anomaly, and a history of inguinal hernia.
Kumiko Tajima   +3 more
wiley   +1 more source

Editorial: Advanced ophthalmic imaging in glaucoma and other optic neuropathies. [PDF]

open access: yesFront Ophthalmol (Lausanne)
Shiga Y   +3 more
europepmc   +1 more source

Immune checkpoint inhibitor‐induced pancreatic enzyme elevation in melanoma patients: Incidence, management and therapy—A multicentre analysis

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
Background, key points, current state of management in dermato‐oncology centres and algorithm for standardized monitoring and management of ICIPI; *routine radiographic imaging according to respective guidelines; **3 months after routine radiographic staging (6‐monthly); ***if not recently performed as part of the routine staging.
M. Brandlmaier   +14 more
wiley   +1 more source

Beyond vision: The emotional toll of advanced diabetic retinopathy

open access: yes
Diabetic Medicine, EarlyView.
Hellena Hailu Habte‐Asres   +2 more
wiley   +1 more source

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