Results 21 to 30 of about 481,902 (329)

Mass spectrometry in ocular drug research

Mass Spectrometry Reviews, EarlyView., 2023
Abstract Mass spectrometry (MS) has been proven as an excellent tool in ocular drug research allowing analyzes from small samples and low concentrations. This review begins with a short introduction to eye physiology and ocular pharmacokinetics and the relevance of advancing ophthalmic treatments.
Eva M. del Amo, Kati‐Sisko Vellonen, Arto Urtti, Tetsuya Terasaki, Anam Hammid, Paavo Honkakoski, Seppo Auriola   +6 more
wiley   +1 more source

Pharmacogenetics of ophthalmic topical β-blockers [PDF]

, 2008
Glaucoma is the second leading cause of blindness worldwide. The primary glaucoma risk factor is elevated intraocular pressure. Topical β-blockers are affordable and widely used to lower intraocular pressure.
McCarty, Catherine A., Patchett, Richard, Sidjanin, Duska J., Smith, Edward M., Wilke, Russell A.   +4 more
core   +1 more source

Trabeculectomy with Suprachoroidal Derivation in Eyes with Uncontrolled Glaucoma: A Case Series with a 24-Month Follow-up

Ophthalmology and Therapy, 2019
Introduction The aim of this study was to evaluate the efficacy of trabeculectomy with suprachoroidal derivation in eyes with uncontrolled glaucoma after a 24-month follow-up period. Methods This was a prospective uncontrolled non-randomized case series.
Rodolfo A. Perez-Grossmann, Daniel E. Grigera, Alan Wenger   +2 more
doaj   +1 more source

Case Report: Reversal and subsequent return of optic disc cupping in a myocilin (MYOC) gene-associated severe Juvenile Open-Angle Glaucoma (JOAG) patient [version 1; peer review: 2 approved]

F1000Research, 2022
To our knowledge, this case report describes the first instance of reversal of glaucomatous optic nerve cupping in a young adult with a rare form of juvenile open-angle glaucoma (JOAG) associated with a novel variant of the myocilin gene (MYOC).
Sanchay Gupta, Cameron Neeson, Hani El Helwe, Sandy Samuel, Marika Chachanidze, David A. Solá-Del Valle   +5 more
doaj   +1 more source

Adapted motivational interviewing to improve the uptake of treatment for glaucoma in Nigeria: study protocol for a randomized controlled trial. [PDF]

, 2014
BACKGROUND: Glaucoma is a chronic eye disease associated with irreversible visual loss. In Africa, glaucoma patients often present late, with very advanced disease.
A Ashaye, A Lam, A Lawan, AE Omoti, AM Agbeja-Baiyeroju, AP Rotchford, AT Giorgis, B Lundahl, BL Burke, Clare Gilbert, CT Ntim-Amponsah, DA Lee, DT La, G Smedslund, H Waterman, HA Quigley, J Lacey, JD Verrey, Jennifer Evans, Jim McCambridge, KP Balo, L Mitcheson, M Kroese, M Mafwiri, MC Leske, MM Abdull, Mohammed M Abdull, N Anand, PF Cook, PJ Foster, RA Charalel, RS Ramrattan, S Rollnick, S Vistamehr, SA Vernon, T Moyers, T Munder, T Wykes, TC Montreuil, The AGIS Investigators, WR Miller, WR Miller   +41 more
core   +3 more sources

Comparison of Phacotrabeculectomy and Phacotrabeculectomy with Subconjunctival 5-Fluorouracil

Journal of Nepal Medical Association, 2014
Introduction: Glaucoma is the second leading cause of blindness worldwide. Phacotrabeculectomy is a technique in which glaucoma and cataract surgery performed.
Nanda Kumari Gurung, Prachand Gautam, Shanti Gurung, Binita Bhattarai   +3 more
doaj   +3 more sources

Disc-Aware Ensemble Network for Glaucoma Screening From Fundus Image [PDF]

IEEE Transactions on Medical Imaging, 2018
Glaucoma is a chronic eye disease that leads to irreversible vision loss. Most of the existing automatic screening methods first segment the main structure and subsequently calculate the clinical measurement for the detection and screening of glaucoma ...
H. Fu, Jun Cheng, Yanwu Xu, Changqing Zhang, D. Wong, Jiang Liu, Xiaochun Cao   +6 more
semanticscholar   +1 more source

Intraocular lens power calculations in eyes with pseudoexfoliation syndrome

Scientific Reports, 2021
To compare refractive outcomes after cataract surgery in pseudoexfoliation syndrome (PEX) and control eyes and to investigate the accuracy of 3 intraocular lens (IOL) calculation formulas in these eyes.
Aleksandra Wlaź, Agnieszka Kustra, Agnieszka Rozegnał-Madej, Tomasz Żarnowski   +3 more
doaj   +1 more source

Glial Cells in Glaucoma: Friends, Foes, and Potential Therapeutic Targets

Frontiers in Neurology, 2021
Glaucoma is the second leading cause of blindness worldwide, affecting ~80 million people by 2020 (1, 2). The condition is characterized by a progressive loss of retinal ganglion cells (RGCs) and their axons accompanied by visual field loss.
M. Y. García-Bermúdez, K. Freude, Z. Mouhammad, P. van Wijngaarden, Keith Martin, M. Kolko   +5 more
semanticscholar   +1 more source

Efficacy and Tolerability of a New Latanoprost 0.005% BAK-Free Nanoemulsion: A Nonrandomized Open-Label Trial

Re:GEN Open, 2021
Purpose: To assess the effectiveness and tolerability of a new latanoprost 0.005% benzalkonium chloride (BAK)-free nanoemulsion. Methods: A nonrandomized multicenter study was conducted between January 2017 and October 2017 in 15 ophthalmological ...
Javier F. Casiraghi, Daniel Grigera, J. Alejo Peyret, Melina del Papa, Mar?a Silvia Passerini   +4 more
doaj   +1 more source