Results 291 to 300 of about 470,158 (371)

Genome-wide association study of intraocular pressure uncovers new pathways to glaucoma

Nature Genetics, 2018
S. Macgregor, Jue-Sheng Ong, Jiyuan An, Xikun Han, Tiger Zhou, O. Siggs, M. Law, Emmanuelle Souzeau, Shiwani Sharma, D. Lynn, J. Beesley, Bronwyn Sheldrick, R. Mills, J. Landers, J. Ruddle, S. Graham, P. Healey, Andrew J. R. White, R. Casson, S. Best, J. Grigg, I. Goldberg, J. Powell, D. Whiteman, G. Radford-Smith, N. Martin, G. Montgomery, K. Burdon, D. Mackey, P. Gharahkhani, J. Craig, A. Hewitt   +31 more
semanticscholar   +1 more source

Premyopia Management With Ophthalmic Referral Slows Myopic Shift After School Entry: A Population‐Based Longitudinal Study in Taiwan

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background This study aimed to evaluate the impact of early ophthalmic referral for premyopic preschoolers on myopic spherical equivalent (SE) shift after school entry; and to identify risk factors for nonadherence to follow‐up care. Methods A population‐based longitudinal study followed 742 premyopic preschoolers (−0.5 D < SE ≤ +0.75 D) from ...
Yu‐Chieh Yang, Hsin‐Yu Yang, Chiao‐Yu Wang, Shao‐You Fang, Chia‐Wei Lee, Pei‐Wei Huang, Mong‐Ping Shyong, Yen‐Lin Chen, Nai‐Wei Hsu, Der‐Chong Tsai   +9 more
wiley   +1 more source

The Relationship Between Macular Pigment Optical Volume and Visual Function in Glaucoma Patients. [PDF]

Invest Ophthalmol Vis Sci
Matsumura N, Asaoka R, Fujino Y, Obana A.   +3 more
europepmc   +1 more source

Vitrectomy as a rapid diagnostic tool for lymphoma: Cytology and flow cytometry approach

British Journal of Haematology, EarlyView.
Pierre Gascon, Diane Frankel, Shirley Fritz, Alban Comet, Frédéric Matonti, Prithvi Ramtohul, John Conrath, Thierry David, Philippe Robert, Laurence Schenone, Vincent Harlay, Olivier Chinot, Emeline Tabouret, Isabelle Nanni, Alexandre Astier, Patrice Roll, Elise Kaspi   +16 more
wiley   +1 more source

Common TGF beta 2, BMP4, and FOXC1 variants are not associated with primary open-angle glaucoma [PDF]

, 2012
Fraser, S, Jamshidi, Y, Park, S, Sowden, JC, Vaideanu, D   +4 more
core  

Identification of Genetic Variants Causing Paediatric Cataract in Myanmar

Clinical Genetics, EarlyView.
Up to 60% of children with cataract in Myanmar have a causative variant in a known cataract gene. This is a similar rate to other populations screened to date, but highlights that there are more cataract genes left to identify. ABSTRACT Genetic testing for paediatric cataract detects a cause in 50%–70% of affected children but is as low as 20% in some ...
Johanna L. Jones, Daisy Boardman, Khine Nweni, Franoli Edo, Isabelly M. Barros de Lima, Pakdhipat Lertsinpakdee, Soe Hlaing, Robert Casson, Ashwin Mallipatna, Ye Win, Bennet McComish, Naing Lin, James Muecke, Andy Griffiths, Martin Holmes, Than Htun Aung, Kathryn P. Burdon   +16 more
wiley   +1 more source

PIK3C2A‐Related Clinical Phenotype and Cellular Charaterization Linked to Functional SHH Primary Cilia Defect

Clinical Genetics, EarlyView.
Trio exome sequencing allowed the identification of two novel compound heterozygous variants in PIK3C2A, defining the fifth family presenting a PIK3C2A‐related syndrome characterized by pulverulent cataracts and deafness. Functional testing revealed impaired PI metabolism and primary dysfunction phenotype.
Adella Karam, Clarisse Delvallée, Bénédicte Gérard, Elodie Javey, Pascal Kessler, Valérie Pelletier, Jean‐Baptiste Lamouche, Nicolas Le May, Jean Muller, Hélène Dollfus   +9 more
wiley   +1 more source

Malignant glaucoma due to dislocated intraocular lens into the vitreous cavity: A case report. [PDF]

Int J Surg Case Rep
Nakayama S, Hirano T, Hanada N, Murata T.   +3 more
europepmc   +1 more source

Deciphering Age‐Dependent ECM Remodelling in Liver: Proteomic Profiling and Its Implications for Aging and Therapeutic Targets

Cell Proliferation, EarlyView.
This study reveals age‐dependent remodelling of the liver extracellular matrix (ECM), identifying Lumican as a key regulator of hepatocyte proliferation and stemness in foetal development. Dynamic ECM shifts influence liver function, offering insights into therapeutic strategies for aging‐related hepatic decline.
Juan Liu, Qingru Song, Chen Li, Jiexin Yan, Ni An, Wenzhen Yin, Jinmei Diao, Yuxin Su, Yunfang Wang   +8 more
wiley   +1 more source