Clinical application of the CO2 laser in Ab externo Schlemm's canal surgery
PurposeThis study aimed to investigate the clinical application of laser as a knife in Ab externo Schlemm's canal (SC) surgery and compare the efficacy and safety of the CO2 laser with the conventional procedure using a surgical knife.MethodsPatients who
Liu Zhang+4 more
doaj +1 more source
An RNA Sequencing Analysis of Glaucoma Genesis in Mice [PDF]
Glaucoma is the leading cause of irreversible blindness in people over the age of 60, accounting for 6.6 to 8% of all blindness in 2010, but there is still much to be learned about the genetic origins of the eye disease. With the modern development of Next-Generation Sequencing (NGS) technologies, scientists are starting to learn more about the genetic
arxiv
Mass spectrometry in ocular drug research
Abstract Mass spectrometry (MS) has been proven as an excellent tool in ocular drug research allowing analyzes from small samples and low concentrations. This review begins with a short introduction to eye physiology and ocular pharmacokinetics and the relevance of advancing ophthalmic treatments.
Eva M. del Amo+6 more
wiley +1 more source
Background To investigate structural and functional correlations in glaucoma patients using enhanced depth imaging spectral-domain optical coherence tomography (EDI OCT)-derived parameters.
Flavio S. Lopes+6 more
doaj +1 more source
GAMMA Challenge:Glaucoma grAding from Multi-Modality imAges [PDF]
Color fundus photography and Optical Coherence Tomography (OCT) are the two most cost-effective tools for glaucoma screening. Both two modalities of images have prominent biomarkers to indicate glaucoma suspected. Clinically, it is often recommended to take both of the screenings for a more accurate and reliable diagnosis.
arxiv
CNNs for automatic glaucoma assessment using fundus images: an extensive validation
Most current algorithms for automatic glaucoma assessment using fundus images rely on handcrafted features based on segmentation, which are affected by the performance of the chosen segmentation method and the extracted features.
A. Diaz-Pinto+5 more
semanticscholar +1 more source
Geometric Deep Learning to Identify the Critical 3D Structural Features of the Optic Nerve Head for Glaucoma Diagnosis [PDF]
Purpose: The optic nerve head (ONH) undergoes complex and deep 3D morphological changes during the development and progression of glaucoma. Optical coherence tomography (OCT) is the current gold standard to visualize and quantify these changes, however the resulting 3D deep-tissue information has not yet been fully exploited for the diagnosis and ...
arxiv
Bangladeshi Case Series of Bardet–Biedl Syndrome
A rare multisystemic, ciliopathic autosomal recessive disorder called Bardet–Biedl syndrome (BBS) primarily affects children of consanguineous marriages. Both men and women are affected by it.
Fariah Osman+3 more
doaj +1 more source
The 3D Structural Phenotype of the Glaucomatous Optic Nerve Head and its Relationship with The Severity of Visual Field Damage [PDF]
$\bf{Purpose}$: To describe the 3D structural changes in both connective and neural tissues of the optic nerve head (ONH) that occur concurrently at different stages of glaucoma using traditional and AI-driven approaches. $\bf{Methods}$: We included 213 normal, 204 mild glaucoma (mean deviation [MD] $\ge$ -6.00 dB), 118 moderate glaucoma (MD of -6.01
arxiv
Retinal Nerve Fiber Layer Features Identified by Unsupervised Machine Learning on Optical Coherence Tomography Scans Predict Glaucoma Progression. [PDF]
Purpose:To apply computational techniques to wide-angle swept-source optical coherence tomography (SS-OCT) images to identify novel, glaucoma-related structural features and improve detection of glaucoma and prediction of future glaucomatous progression.
Belghith, Akram+7 more
core +1 more source