Results 221 to 230 of about 57,809 (287)

Power and clinical utility of mesopic microperimetry analysis strategies in age‐related macular degeneration

Acta Ophthalmologica, Volume 104, Issue 3, Page e292-e299, May 2026.
Abstract Purpose This study evaluates whether mesopic microperimetry (MMP) provides a more robust measure of retinal function compared to visual acuity (VA) in age‐related macular degeneration (AMD) clinical trials, with a focus on optimal analysis strategies. Method Fellow‐eyes of unilateral neovascular AMD were prospectively studied.
Francesco Cinque, Jeroen Pas, Mahfam Shahabi, Laurens Sluijterman, Sofie ten Brink, Anita de Breuk, Thomas J. Heesterbeek, Caroline Klaver, Carel Hoyng, Yara Lechanteur   +9 more
wiley   +1 more source

Exploring the histopathological signature of repeat‐mediated Fuchs endothelial corneal dystrophy

Acta Ophthalmologica, Volume 104, Issue 3, Page 333-341, May 2026.
Abstract Purpose To determine the histological differences between Fuchs endothelial corneal dystrophy (FECD) cases with and without the most common genetic risk factor, expansion of a CTG repeat (CTG18.1) within the TCF4 gene. Methods Formalin‐fixed paraffin‐embedded corneal tissues were compared retrospectively, and CTG18.1 status was determined from
Anne‐Marie S. Kladny, Nihar Bhattacharyya, Marcos Abreu Costa, Stephen J. Tuft, Caroline Thaung, Alice E. Davidson   +5 more
wiley   +1 more source

Sociodemographic and Clinical Determinants of Glaucoma in a Sub-Saharan African Population: A Case-Control Study. [PDF]

Health Sci Rep
Ampong A, Lartey S, Tagoe NN, Essuman YA, Abaidoo B, Beyuo VM, Owusu-Asare LP, Ofori-Adjei DI, Essuman VA.   +8 more
europepmc   +1 more source

Advances in the genetics of refractive errors: Contributions from the CREAM consortium

Acta Ophthalmologica, Volume 104, Issue 3, Page e222-e231, May 2026.
Abstract The Consortium for Refractive Error and Myopia (CREAM) was established in 2011, bringing together an international team of researchers studying more than 30 cohorts. Since its establishment, CREAM has played a pivotal role in research investigating the genetics of myopia and other refractive errors, serving as a key driver of progress in the ...
Sze Wai Rosa Li, Xi He, Louise Terry, Virginie J. M. Verhoeven, Samantha Sze‐Yee Lee, Gareth Lingham, Jeremy A. Guggenheim, David A. Mackey, Seang‐Mei Saw, Caroline C. W. Klaver, Chi Pui Pang, CREAM Consortium   +11 more
wiley   +1 more source

Sectoral Analysis of Corneal Thickness in Glaucoma and Healthy Eyes and Its Relationship with RNFL and Rim Area. [PDF]

J Clin Med
Miklaszewski P, Gadamer AM, Lelek Z, Janiszewska-Bil D, Lyssek-Boroń A, Dobrowolski D, Wylęgała E, Grabarek BO, Koss MJ, Krysik K.   +9 more
europepmc   +1 more source

Blindness and prognostic factors after trabeculectomy with mitomycin C in patients with open‐angle glaucoma with long‐term follow‐up

Acta Ophthalmologica, Volume 104, Issue 3, Page e232-e238, May 2026.
Abstract Purpose To determine the long‐term blindness rate and related prognostic factors in eyes with open‐angle glaucoma after trabeculectomy using adjunctive mitomycin C (MMC). Methods The retrospective cohort study included 714 eyes from 714 patients with open angle glaucoma who underwent trabeculectomy using MMC.
Masato Matsuo, Akira Sawada, Taishi Miyase, Masayuki Inuzuka, Masaomi Kubota, Tetsuya Yamamoto   +5 more
wiley   +1 more source

Association of ocular symptom burden with sleep quality and psychological distress in patients with primary glaucoma: A cross-sectional study. [PDF]

Medicine (Baltimore)
Wang W, Wang Y.
europepmc   +1 more source

Novel drugs approved by the EMA, the FDA and the MHRA in 2025: A year in review

British Journal of Pharmacology, Volume 183, Issue 9, Page 1779-1813, May 2026.
Abstract In the 2025 novel drug mini‐review, one can take a full measure of the ingenuity that underlies current drug design and development, despite the year's smaller harvest (46 novel drugs) compared to 2024 (53) and 2023 (70). 54% of the novel drugs are first‐in‐class (FIC).
Andreas Papapetropoulos, Stavros Topouzis, Steve P. H. Alexander, Miriam M. Cortese‐Krott, Zsuzsanna Helyes, Kirill Martemyanov, Claudio Mauro, Nithyanandan Nagercoil, Reynold A. Panettieri Jr, Hemal H. Patel, Rainer Schulz, Barbara Stefanska, Gary J. Stephens, Nathalie Vergnolle, Xin Wang, Stephen Ward, Péter Ferdinandy   +16 more
wiley   +1 more source

Healthcare Utilisation in Ageing Adults With Intellectual Disability: Longitudinal Evidence From Five Waves of IDS‐TILDA

Journal of Applied Research in Intellectual Disabilities, Volume 39, Issue 3, May 2026.
ABSTRACT Background Adults with intellectual disability are living longer and ageing with more illness. This impacts healthcare utilisation. Yet little is known about how healthcare utilisation changes over time as this population ages. Methods Five waves of longitudinal data of people ≥ 40 years with intellectual disability from 2009 to 2023 were ...
Martin McMahon, Aviejay Paul, Catriona Ryan, Louise Lynch, Philip McCallion, Mary McCarron, Eilish Burke   +6 more
wiley   +1 more source

Efficacy and safety of Kahook dual blade glide in Indian patients with glaucoma. [PDF]

Indian J Ophthalmol
Mansoori T.
europepmc   +1 more source