Results 121 to 130 of about 98,217 (221)
Senescence‐Driven IL‐17A Inflammatory Circuit Promotes Epithelial–Mesenchymal Transition (EMT) and Progression in Age‐Related Posterior Subcapsular Cataracts
Aging Cell, Volume 25, Issue 4, April 2026.Using multi‐region human PSC samples, we identified EMT as a consistent pathological feature. Mechanistically, senescent LECs secrete IL‐17A, a representative SASP factor, which activates NF‐κB signaling. NF‐κB further amplifies SASP production, thereby establishing a senescence–inflammation feedback loop that drives EMT, sustains pathological ...Yan Ni, Yu Ma, Zewen Ren, Yi Zhu, Liangping Liu, Runping Duan, Lu Qin, Yang Chen, Rong Ju, Yingyan Qin, Mingxing Wu +10 morewiley +1 more sourceAllergic Rhinitis and Its Impact on Asthma (ARIA)‐EAACI Guidelines—2024–2025 Revision: Part I—Guidelines on Intranasal Treatments
Allergy, Volume 81, Issue 4, Page 954-976, April 2026.ABSTRACT Background
Allergic rhinitis (AR) impacts quality of life, work and school productivity. Over the last years, an important body of evidence resulting from mHealth data has led to a better understanding of AR. Such advances have motivated an EAACI‐endorsed update of the Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines (ARIA 2024 ...Bernardo Sousa‐Pinto, Jean Bousquet, Rafael José Vieira, Holger J. Schünemann, Torsten Zuberbier, Antonio Bognanni, Alkis Togias, Boleslaw Samolinski, Arunas Valiulis, Sian Williams, Anna Bedbrook, Wienczyslawa Czarlewski, Maria Jose Torres, Mohamed H. Shamji, Mário Morais‐Almeida, G. Walter Canonica, Leticia de las Vecillas, Mark S. Dykewicz, Cristina Jacomelli, Ludger Klimek, Lucas Leemann, Olga Lourenço, Yuliia Palamarchuk, Nikolaos G. Papadopoulos, Ana Margarida Pereira, Marine Savouré, Sanna K. Toppila‐Salmi, Maria Teresa Ventura, Juan José Yepes‐Nuñez, Alvaro A. Cruz, Giorgio Ciprandi, Bilun Gemicioglu, Mattia Giovannini, Brigita Gradauskiene, Tuomas Jartti, Miloš Jeseňák, Piotr Kuna, Violeta Kvedariene, Désirée E. Larenas‐Linnemann, Amir HA Latiff, Yousser Mohammad, Ken Ohta, Padukudru A. Mahesh, Isabella Pali‐Schöll, Oliver Pfaar, Frederico S. Regateiro, Nicolas Roche, Luís Taborda‐Barata, Charlotte Suppli Ulrik, Marylin Valentin Rostan, Giovanni Viegi, Luo Zhang, Tari Haahtela, Ivan Cherrez‐Ojeda, Juan Carlos Ivancevich, Nikolai Khaltaev, Arzu Yorgancioglu, Baharudin Abdullah, Mona Al‐Ahmad, Maryam Ali Al‐Nesf, Rita Amaral, Julijana Asllani, Karl‐C Bergmann, Jonathan A. Bernstein, Michael S. Blaiss, Fulvio Braido, Paulo Camargos, Pedro Carreiro‐Martins, Thomas Casale, Lorenzo Cecchi, Alessandro Fiocchi, Antonio F. M. Giuliano, George Christoff, Ieva Cirule, Jaime Correia de Sousa, Elisio M. Costa, Stefano Del Giacco, Philippe Devillier, Dejan Dokic, Elham Hossny, Tomohisa Iinuma, Carla Irani, Zhanat Ispayeva, Kaja Julge, Igor Kaidashev, Kazi S. Bennoor, Helga Kraxner, Inger Kull, Marek Kulus, Maciej Kupczyk, Andriy Kurchenko, Stefania La Grutta, Neven Miculinic, Lan Le Thi Tuyet, Michael Makris, Branislava Milenkovic, Sang Min Lee, Stephen Montefort, Andre Moreira, Joaquim Mullol, Rachel Nadif, Alla Nakonechna, Hugo E. Neffen, Marek Niedoszytko, Dieudonné Nyembue, Robyn E. O'Hehir, Ismail Ogulur, Yoshitaka Okamoto, Heidi Olze, Oscar Palomares, Petr Panzner, Vincenzo Patella, Ruby Pawankar, Constantinos Pitsios, Todor A. Popov, Francesca Puggioni, Santiago Quirce, Agné Ramonaité, Marysia Recto, Maria Susana Repka‐Ramirez, Graham Roberts, Karla Robles‐Velasco, Menachem Rottem, Marianella Salapatas, Joaquin Sastre, Nicola Scichilone, Juan‐Carlos Sisul, Dirceu Solé, Manuel E. Soto‐Martinez, Milan Sova, Pongsakorn Tantilipikorn, Ana Todo‐Bom, Vladyslav Tsaryk, Ioanna Tsiligianni, Marilyn Urrutia‐Pereira, Erkka Valovirta, Tuula Vasankari, Dana Wallace, De Yun Wang, Margitta Worm, Osman M. Yusuf, Mihaela Zidarn, Sara Gil‐Mata, Manuel Marques‐Cruz, Bassam Mahboub, Ignacio J. Ansotegui, Antonino Romano, Werner Aberer, Maria Cristina Artesani, Elena Azzolini, Bruno Barreto, Joan Bartra, Sven Becker, Bianca Beghe, Attilio Boner, Ewa Borowiack, Jacques Bouchard, Melisande Bourgoin‐Heck, Luisa Brussino, Roland Buhl, José Antonio Castillo‐Vizuete, Denis Charpin, Niels H. Chavannes, Marta Chełmińska, Lei Cheng, Ekaterine Chkhartishvili, Seong H. Cho, Herberto Jose Chong‐Neto, Deepa Choudhury, Derek K. Chu, Cemal Cingi, Enrico Compalati, Raquel Albuquerque Costa, Olga Mariana Cunha, Biljana Cvetkovski, Victoria Cardona‐Dahl, Gennaro D'Amato, Janet Davies, Danilo Di Bona, Sandra N. Gonzalez Diaz, Maria V. Dimou, Maria Doulaptsi, Renato Ferreira‐da‐Silva, Radoslaw Gawlik, Mario Calvo‐Gil, Ozlem Goksel, Maximiliano R. Gómez, Maia Gotua, Christos Grigoreas, Ineta Grisle, Maria Antonieta Guzman, Rachel House Tan, Michael Hyland, Despo Ierodiakonou, Aspasia Karavelia, Paul Keith, Marta Kisiel, Tanja Soklic Kosak, Mitja Kosnik, Ilgim Vardaloglu Koyuncu, Vicky Kritikos, Justyna Litynska, Carlo Lombardi, Gilles Louis, Matteo Martini, Cem Meço, Eris Mesonjesi, Florin Mihaltan, Marcin Moniuszko, Robert N. Naclerio, Kari C. Nadeau, Sophia Neisinger, Markus Ollert, Michal Ordak, Giovanni Paoletti, Hae‐Sim Park, Elena Parmelli, Edgar Arturo Perdomo‐Flores, José Miguel Fuentes Pérez, Nhan Pham‐Thi, Emmanuel Prokopakis, Inês Ribeiro‐Vaz, Giovanni Rolla, Jan Romantowski, Philippe Rombaux, Philip W. Rouadi, Maia Rukhadze, Dermot Ryan, Ewelina Sadowska, Daiju Sakurai, Laila Salameh, Faradiba Serpa Sarquis, Elie Serrano, Jane Da Silva, Michael Soyka, Krzysztof Specjalski, Vesna Tomic‐Spiric, Katarina Stevanovic, Abirami Subramaniam, Maria Do Ceu Teixeira, Tuuli Thomander, Martina Vachova, Marianne van Hage, Pakit Vichyanond, Martin Wagenmann, Fanny Wai San Ko, Pascal Werminghaus, Paraskevi Vicky Xepapadaki, Yi‐Kui Xiang, Qintai Yang, Daniela Rivero Yeverino, Jaron Zuberbier, João A. Fonseca +252 morewiley +1 more sourceThe Phenotypic and Genotypic Features of ADAMTSL4‐Related Ocular Disease
Clinical Genetics, Volume 109, Issue 4, Page 730-741, April 2026.ADAMTSL4‐related ocular disease tends to present at a younger age and be associated with higher myopia than other forms of ectopia lentis (such as FBN1). A previously reported 20‐bp deletion (c.767_786del) was highly prevalent in this cohort (23/32), and all ectopia lentis et pupillae cases carried this variant. ABSTRACT
Pathogenic variants in ADAMTSL4 Katie M. Williams, Wolfgang Berger, Samuel Koller, Fatma Kivrak Pfiffner, Alessandro Maspoli, Jiradet Gloggnitzer, Britta V. T. Brühwiler, Christina Stathopoulos, Francis Munier, Louise Allen, Christos Iosifidis, Graeme C. Black, Panagiotis I. Sergouniotis, Ian Christopher Lloyd, Christina Gerth‐Kahlert +14 morewiley +1 more sourceOcular movement abnormalities and ptosis after glaucoma surgery: A retrospective decade long analysis. [PDF]
PLoS OneCatti C, Tessitore F, Ferrari D, Milanesi F, Acerra S, Peci L, Rizzi A, Semeria S, Schiavetti I, Cutolo CA, Iester M, Vagge A. +11 moreeuropepmc +1 more sourceA Realist Evaluation of the Implementation and Use of Patient‐Reported Outcomes in Four Value‐Based Healthcare Programmes
Journal of Advanced Nursing, Volume 82, Issue 4, Page 3678-3701, April 2026.ABSTRACT Aim
To investigate what works when using Patient‐Reported Outcome Measures (PROMs), for whom, in what contexts, and why in four Value‐Based Healthcare (VBHC) programmes. Design
Realist evaluation. Methods
Evaluation of Heart Failure, Parkinson's Disease, Epilepsy and Cataract surgery programmes using data from a scoping review, documentary ...Mayara S. Bianchim, Ellie Crane, Leah McLaughlin, Carys Stringer, Gareth Roberts, Adele Cahill, Jane Noyes +6 morewiley +1 more source
