Results 61 to 70 of about 1,596,619 (295)

Engineering mRNA‐LNP Medicines for the Ageing Brain: Opportunities and Challenges for Neurodegenerative Diseases

Exploration, EarlyView.
This review highlights recent advances in engineering messenger RNA (mRNA)‐lipid nanoparticles (LNPs) to cross the ageing blood–brain barrier and target neurodegenerative diseases. It outlines design principles, delivery routes, and translational challenges, charting a roadmap towards clinical application of mRNA‐LNP therapeutics for neurodegenerative ...
Abdel Ali Belaidi, Denzil L. Furtado, Francesca Alves, Rebecca M. Nisbet, Scott Ayton, Ashley I. Bush   +5 more
wiley   +1 more source

Minimally Invasive Glaucoma Surgery (MIGS) for individuals with glaucoma. A health technology assessment [PDF]

, 2021
Key messages: This health technology assessment (HTA) summarises and supplements a 2019 Canadian HTA on the effectiveness and safety of micro-invasive glaucoma surgery (MIGS) versus other treatment options.
Lerner, Martin Robert, Reinar, Liv Merete Brynildsen, Lund, Ulrikke Højslev, Bidonde, Julia, Kvist, Beate Charlotte Fagerlund, Ursin, Lars Øystein, Kornør, Hege, Nguyen, Lien, Robberstad, Bjarne   +8 more
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Short‐Term Outcomes of Two Interventions for Patients With Active Proliferative Diabetic Retinopathy in an Urban, Safety‐Net Hospital

Health Care Science, EarlyView.
An additional weekly resident‐run panretinal photocoagulation (PRP) clinic and implementation of a high‐risk registry and appointment system were associated with a decreased wait time from proliferative diabetic retinopathy (PDR) diagnosis to PRP, increased 3‐month PRP completion rates, decreased 3‐month loss to follow‐up, and increased ophthalmology ...
Paul S. Micevych, Abu Tahir Taha, Anika Kumar, Jay M. Stewart   +3 more
wiley   +1 more source

Association between periodontitis and exudative retinal detachment: A population‐based cohort study

Journal of Periodontology, EarlyView.
Abstract Background To investigate whether periodontitis, a common bacterial‐induced inflammatory condition, serves as a risk factor for exudative retinal detachment (ERD), which results from fluid entering the subretinal space due to damage to the retinal pigment epithelium or leaky intraocular vessels, typically associated with inflammatory ...
Earl Fu, Ming‐Ling Tsai, Tsu‐Hsuan Weng, Chi‐Hsiang Chung, Min‐Wen Fu, Wu‐Chien Chien   +5 more
wiley   +1 more source

Nationwide incidence of and risk factors for undergoing incisional glaucoma surgery following infantile cataract surgery

Scientific Reports
Nationwide incidence and risk factors for incisional glaucoma surgery post-infantile cataract (IC) surgery in children remain poorly understood. We conducted a population-based cohort study using the Korean national health claims database to identify IC ...
Sooyeon Choe, Young Kook Kim, Ahnul Ha
doaj   +1 more source

Rethinking Age Limits in Oncoplastic Breast Surgery: Long‐Term Outcomes of Oncoplastic Surgery in Elderly Patients

Journal of Surgical Oncology, EarlyView.
ABSTRACT Background and Methods Although OBS is a well‐established approach, evidence regarding its long‐term safety and outcomes in older women remains limited. We performed a retrospective analysis to identify patients ≥ 60 years who underwent OBS for breast cancer between 2001 and 2014.
Francesca De Lorenzi, Sergio Miranda, Eleonora Pagan, Vincenzo Bagnardi, Claudia Sangalli, Martina Lo Cascio, Martina Quinteri, Fernando Rosatti, Giulio Tarantino, Paolo Veronesi   +9 more
wiley   +1 more source

Combined Baerveldt glaucoma drainage implant surgery and surgical bleb revision for preventing a postoperative hypertensive phase [PDF]

, 2014
オープンアクセス CC-BY-NCBACKGROUND: In patients with severe optic nerve damage, it is crucial to prevent the hypertensive phase that can develop after Baerveldt glaucoma drainage implant (BGI) surgery.
ヨシダ, アキトシ, Yamaguchi, Toru, Yoshida, Akitoshi, 中林, 征吾, 吉田, 晃敏, カワイ, モトフミ, Kawai, Motofumi, ナカバヤシ, セイゴ, 川井, 基史, ヤマグチ, トオル, Nakabayashi, Seigo, 山口, 亨, Kawai M, Yoshida A, Yamaguchi T, Nakabayashi S   +15 more
core   +2 more sources

Optic Nerve Thickness Assessed by Ocular Ultrasonography in Obstructive Sleep Apnea

Journal of Ultrasound in Medicine, EarlyView.
Objectives Obstructive sleep apnea (OSA) has been associated with various ocular complications, yet ultrasonographic evaluation of optic nerve thickness and its relationship with nocturnal hypoxemia remains poorly understood. This study aimed to evaluate optic nerve thickness and globe dimensions using ocular ultrasonography in patients with different ...
Buğra Kerget, Eyüp Çetin, Alperen Aksakal, Sırma Merve Çetin, Mustafa Buğra Coşkuner   +4 more
wiley   +1 more source

Glaucoma drainage device implantation and cyclophotocoagulation in the management of refractory glaucoma after Descemet-stripping automated endothelial keratoplasty [PDF]

International Journal of Ophthalmology
AIM: To compare the surgical outcomes of glaucoma drainage device implantation (GDI) and trans-scleral neodymium:YAG cyclophotocoagulation (CPC) in the management of refractory glaucoma after Descemet-stripping automated endothelial keratoplasty (DSAEK).
Min-Shu Wang, Xue-Chuan Dong, Mi-Yun Zheng, Xiang Fan, Ge-Ge Xiao, Jing Hong, Ling-Ling Wu   +6 more
doaj   +1 more source

Ptosis after glaucoma surgery

, 2017
Abraham J Park,1 Babak Eliassi-Rad,2 Manishi A Desai2 1Moyes Eye Center, Department of Ophthalmology, 2Boston Medical Center, Department of Ophthalmology, Boston, MA, USA Purpose: Evaluate factors contributing to ptosis after glaucoma surgery. Methods:
Desai MA, Eliassi-Rad B, Park AJ
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