Results 191 to 200 of about 13,935 (294)

Rapid generation of prion disease models using AAV‐delivered PrP variants in knockout mice

open access: yesBrain Pathology, Volume 36, Issue 4, July 2026.
We developed a rapid AAV‐based system to generate prion disease models in weeks rather than months. Following systemic AAV9P31 delivery of modified PrP to knockout mice, we achieved brain‐wide expression and successful propagation of both classical (RML) and atypical (GSS‐A117V) prion strains.
Maitena San‐Juan‐Ansoleaga   +11 more
wiley   +1 more source

Offspring Size Resolves a Population Growth Paradox in Rays and Skates

open access: yesFish and Fisheries, Volume 27, Issue 4, Page 927-941, July 2026.
ABSTRACT The maximum intrinsic population growth rate, rmax, is a key determinant of sustainable fishing limits and is increasingly used in risk assessments. We previously showed how the rmax of rays and skates (subclass Batoidea) scales with adult body size, temperature (and hence depth) such that smaller‐bodied species and those in warmer, shallower ...
Ellen Barrowclift   +4 more
wiley   +1 more source

The Influence of Different Polishing Systems on the Gloss and Surface Roughness of Two Distinct Nano‐Filled Composites

open access: yesJournal of Esthetic and Restorative Dentistry, Volume 38, Issue 7, Page 1448-1457, July 2026.
ABSTRACT Objective To evaluate the influence of different polishing systems on the surface roughness and gloss of two nano‐filled resin composites, and to investigate the effect of a modeling agent (Ceramage) on surface roughness. Methods Two nano‐filled resin composites, Filtek Z350 XT and Palfique LX5, were used.
Abdulrahman Alghamdi, Hanan Filemban
wiley   +1 more source

The myth of the metabolic baseline: sleep–wake cycles undermine a foundational assumption in organismal biology

open access: yesBiological Reviews, Volume 101, Issue 3, Page 1491-1510, June 2026.
ABSTRACT Basal and standard metabolic rate (BMR and SMR) are cornerstones of physiological ecology and are assumed to be relatively fixed intrinsic properties of organisms that represent the minimum energy required to sustain life. However, this assumption is conceptually flawed. Many core maintenance processes underlying SMR are temporally partitioned
Helena Norman   +4 more
wiley   +1 more source

Evaluating the Intercropping Systems in the Context of Agroecological Resilience in the Current Era of the Changing Climate: A Scenario of Scientific Analysis of Last Decade Data

open access: yesClimate Resilience and Sustainability, Volume 5, Issue 1, June 2026.
The extreme event of climate change (CC) has become more crucial, and under the current context of CC during the last decade. The cropping system (CS) approach is more appropriate than a suitable and established package of practices for individual crops, as CS interrelates with other components and resources related to sustainable farming under the ...
Sagar Maitra   +9 more
wiley   +1 more source

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