Results 281 to 290 of about 412,622 (340)

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

Epilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang, Emilio Perucca, Samuel F. Berkovic, Piero Perucca   +3 more
wiley   +1 more source

Nasal Glioma

, 1976
Masako HIRANO, Isao TAKIMOTO, Shigeru INAFUKU, Kazumi Yamada, Masau HANDOH, Mitsuharu YOSHIDA   +5 more
openalex   +2 more sources

Correction to: Glioma-derived SPARCL1 promotes the formation of peritumoral neuron-glioma synapses. [PDF]

J Neurooncol
Li Y, Wang Y, Han X, Xu J, Liu E, Cheng J, Ma Y, Yang T, Wu J, Sun H, Fan K, Shen D, Li J, Chen X, Yu S, Shu H.   +15 more
europepmc   +1 more source

NIR II‐Guided Photoactivatable Silencing Polyplex Boosts Cancer Immunotherapy

Exploration, EarlyView.
Due to limitation of penetration therapy with first and second‐generation photodynamic therapy (PDT) photosensitizers, an NIR II‐guided photoactivatable complex was proposed via the self‐assembly of the photosensitive polymer PTSQ and the electrostatic adsorption of siPD‐L1 to enhance cancer immunotherapy.
Yuquan Zhang, Jie Wang, Tian Zhang, Dongsheng Tang, Haiyin Yang, Shuai Guo, Yuchuan Fan, Caixia Sun, Haihua Xiao, Yuanyu Huang, Yuhua Weng   +10 more
wiley   +1 more source

TMEM115: a promising marker for glioma immunotherapy and prognosis. [PDF]

Front Immunol
Yin H, Wang F, Xu H, Xu M, Lu P, Zhang X, Yang L, Lu B, Sun P, Huang J.   +9 more
europepmc   +1 more source

Deciphering the Potential Causal and Prognostic Relationships Between Gut Microbiota and Brain Tumors: Insights from Genetics Analysis and Machine Learning

Exploration, EarlyView.
The causal relationship between gut microbiota and brain tumors and potential prognostic value of microbiota are still unclear. This study confirmed the causal effects of specific gut microbiota on three common brain tumors and identified microbe‐related genes that are expressed in brain tissue and correlated with the abundance of gut microbiota ...
Changwu Wu, Fushu Luo, Yongye Zhu, Chunbo Liu, Zheng Chen, Xiangyu Wang, Jun Tan, Qing Liu   +7 more
wiley   +1 more source

Clusterin facilitates glioma progression via BCL2L1-dependent regulation of apoptotic resistance. [PDF]

Front Mol Neurosci
Xu Q, Liu X, Zhang Y, Yuan S, Huang W, Pi M, Xiong Q, Zhou H, Gui Y, Xiao Y, Wang X, Shu X, Xia Y.   +12 more
europepmc   +1 more source

Emerging Target Discovery Strategies Drive the Decoding of Therapeutic Power of Natural Products and Further Drug Development: A Case Study of Celastrol

Exploration, EarlyView.
Using celastrol as a case study, this review summarizes various target discovery strategies for natural products, including chemical proteomics, protein microarray, degradation‐based protein profiling, proteome‐wide label‐free approaches, network pharmacology, target‐based drug screening, and indirect strategies.
Yanbei Tu, Guiyu Dai, Yanyan Chen, Lihua Tan, Hanqing Liu, Meiwan Chen   +5 more
wiley   +1 more source

A tumor microenvironment model for glioma diagnosis and therapeutic evaluation based on the analysis of tissues and biological fluids. [PDF]

iScience
Zhang Q, Chi H, Qi Y, Zhao R, Xue F, Li G, Xue H.   +6 more
europepmc   +1 more source