Results 11 to 20 of about 169,224 (213)

Glioma [PDF]

Nature Reviews Disease Primers, 2015
Gliomas are primary brain tumours that are thought to derive from neuroglial stem or progenitor cells. On the basis of their histological appearance, they have been traditionally classified as astrocytic, oligodendroglial or ependymal tumours and assigned WHO grades I-IV, which indicate different degrees of malignancy.
Weller, Michael, Wick, Wolfgang, Aldape, Ken, Brada, Michael, Berger, Mitchell, Pfister, Stefan M, Nishikawa, Ryo, Rosenthal, Mark, Wen, Patrick Y, Stupp, Roger, Reifenberger, Guido   +10 more
openaire   +4 more sources

CHI3L2 Is a Novel Prognostic Biomarker and Correlated With Immune Infiltrates in Gliomas

Frontiers in Oncology, 2021
CHI3L2 (Chitinase-3-Like Protein 2) is a member of chitinase-like proteins (CLPs), which belong to the glycoside hydrolase 18 family. Its homologous gene, CHI3L1, has been extensively studied in various tumors and has been shown to be related to immune ...
Liling Liu, Liling Liu, Yuanzhong Yang, Yuanzhong Yang, Hao Duan, Hao Duan, Jiahua He, Jiahua He, Lu Sun, Lu Sun, Wanming Hu, Wanming Hu, Jing Zeng, Jing Zeng   +13 more
doaj   +1 more source

ADAMDEC1 accelerates GBM progression via activation of the MMP2-related pathway

Frontiers in Oncology, 2022
The ADAM (a disintegrin and metalloprotease) gene-related family including ADAM, ADAMTS, and ADAM-like decysin-1 has been reported to play an important role in the pathogenesis of multiple diseases, including cancers (lung cancer, gliomas, colorectal ...
Huimin Qi, Ping Wang, Hongliang Sun, Xiaohan Li, Xinwei Hao, Wenxiu Tian, Wenxiu Tian, Liting Yu, Jiajian Tang, Junhong Dong, Hongmei Wang, Hongmei Wang   +11 more
doaj   +1 more source

Morphological Patterns of Intracranial Lesions in a Tertiary Care Hospital in North Karnataka: A Clinicopathological and Immunohistochemical Study [PDF]

Journal of Clinical and Diagnostic Research, 2016
Introduction: An “Intra-cranial space occupying lesion” (ICSOL) is defined as a mass lesion in the cranial cavity with a diverse aetiology like benign or malignant neoplasm, inflammatory or parasitic lesion, haematoma, or arterio-venous malformation.
HEMA NEELAKANTAIAH ANADURE, RAMDURG SHASHANK RAVINDRA, ANDOLA SAINATH KARNAPPA   +2 more
doaj   +1 more source

Real-time quantitative polymerase chain reaction assay for detecting 1p and 19q codeletion in glioma

Biomedical and Biotechnology Research Journal, 2023
Background: Glioma is a type of tumor that occurs in the brain and spinal cord. Gliomas begin in the gluey supportive cells (glial cells) that surround nerve cells and help them function.
Niem Van Thanh Vo, Diem Dinh-Kieu Truong, Phan Thi Xinh, Hoang Anh Vu   +3 more
doaj   +1 more source

Regression/eradication of gliomas in mice by a systemically-deliverable ATF5 dominant-negative peptide. [PDF]

, 2016
Malignant gliomas have poor prognosis and urgently require new therapies. Activating Transcription Factor 5 (ATF5) is highly expressed in gliomas, and interference with its expression/function precipitates targeted glioma cell apoptosis in vitro and in ...
Angelastro, James, Arias, Angelo, Cates, Charles, Cayanan, Geraldine, Fung, Jennifer, Greene, Lloyd, Karpel-Massler, Georg, Lamé, Michael, Nakayama Wong, Lynn, Rowland, Douglas, Sidorov, Maxim, Siegelin, Markus   +11 more
core   +2 more sources

Hypoxia helps glioma to fight therapy [PDF]

, 2009
Despite major improvements in the surgical management the prognosis for patients bearing malignant gliomas is still dismal. Malignant gliomas are notoriously resistant to treatment and the survival time of patients is between 3-8 years for low-grade and
Amberger-Murphy, Verena
core   +1 more source

Thermodynamics in Gliomas: Interactions between the Canonical WNT/Beta-Catenin Pathway and PPAR Gamma

Frontiers in Physiology, 2017
Gliomas cells are the site of numerous metabolic and thermodynamics abnormalities with an increasing entropy rate which is characteristic of irreversible processes driven by changes in Gibbs energy, heat production, intracellular acidity, membrane ...
Alexandre Vallée, Alexandre Vallée, Yves Lecarpentier, Rémy Guillevin, Jean-Noël Vallée, Jean-Noël Vallée   +5 more
doaj   +1 more source

AVNP2 protects against cognitive impairments induced by C6 glioma by suppressing tumour associated inflammation in rats [PDF]

, 2020
© 2020 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/BY-NC-ND/4.0/).Glioblastoma is a kind of malignant tumour and originates from the central nervous system.
Bankier, Barkal, Barria, Benros, Braganhol, Campos-Pires, Chen, Cheong, Chicoine, Crossen, D'Alessandris, d'Isa, da Silva, Dalton, Del Sol-Fernandez, Ferrandon, Froklage, Gong, Graf, Graus, Guogang Ren, Hao, Hara, He, Heppner, Hilverda, Hwang, Jacob, Janelsins, Ji, Jin Gao, Junyang Li, Lang, Liang, Limin Wu, Liu, McFarland, Meicen Liu, Meng, Mineharu, Mostofa, Murata, Myung, Nagano, Nan, Nan, Noy, Oh, Ohgaki, Okada, Ostrom, Ovais, Park, Parrott, Platten, Quant, Reichel, Reid, Ren, Ren, Ren, Saalik, Shan, Sholl, Sim, Solanki, Sorensen, Sorra, Spacek, Stupp, Stupp, Tanaka, Thompson, Thorsson, Van Dyk, Vecht, Venkatesh, Walker, Walker Ii, Wan, Wang, Wang, Weitzner, Williams, Woodward, Wu, Wu, Yang, Yang, Yang, Yang, Yu, Yu Jiang, Yuen-Ki Cheong, Zhang, Zhu, Zhuo Yang, Zong, Zou   +98 more
core   +2 more sources

Small Interfering RNA for Gliomas Treatment: Overcoming Hurdles in Delivery

Frontiers in Cell and Developmental Biology, 2022
Gliomas are central nervous system tumors originating from glial cells, whose incidence and mortality rise in coming years. The current treatment of gliomas is surgery combined with chemotherapy or radiotherapy. However, developing therapeutic resistance
Xin-Qi Teng, Xin-Qi Teng, Xin-Qi Teng, Jian Qu, Guo-Hua Li, Hai-Hui Zhuang, Qiang Qu, Qiang Qu   +7 more
doaj   +1 more source