Results 11 to 20 of about 127,720 (302)

Gliomas in Children

Seminars in Neurology, 2018
AbstractGliomas are the most common primary central nervous system (CNS) neoplasms in children and adolescents and are thought to arise from their glial progenitors or stem cells. Although the exact cells of origin for most pediatric gliomas remain to be identified, our current understanding is that specific cell populations during CNS development are ...
Mariella G, Filbin, Dominik, Sturm
openaire   +3 more sources

Glioma [PDF]

Nature Reviews Disease Primers, 2015
Gliomas are primary brain tumours that are thought to derive from neuroglial stem or progenitor cells. On the basis of their histological appearance, they have been traditionally classified as astrocytic, oligodendroglial or ependymal tumours and assigned WHO grades I–IV, which indicate different degrees of malignancy.
Weller, Michael, Wick, Wolfgang, Aldape, Ken, Brada, Michael, Berger, Mitchell, Pfister, Stefan M, Nishikawa, Ryo, Rosenthal, Mark, Wen, Patrick Y, Stupp, Roger, Reifenberger, Guido   +10 more
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Clinical Impact of MGMT Promoter Methylation in IDH-Mutant Gliomas: Influence of Threshold Selection and Clinical Confounding. [PDF]

Ann Clin Transl Neurol
ABSTRACT Background The clinical relevance of MGMT promoter methylation in IDH‐mutant gliomas remains controversial in the era of molecular classification. We aimed to systematically evaluate its clinical relevance by integrating quantitative assessment, cutoff exploration, and adjustment for clinical confounding.
Jiang H, Cao L, Chen X, Tong S, Zhu Q, Yang J, Lin S, Cui Y.   +7 more
europepmc   +2 more sources

Neutrophils in Gliomas [PDF]

Frontiers in Immunology, 2017
Neutrophils are the most abundant white blood cells and are the first recruited to inflammatory sites. Neutrophils are an important component of the tumor stroma and can exert both anti-tumoral and pro-tumoral activities, depending on their maturation and activation state.
Matteo Massara, Matteo Massara, Pasquale Persico, Ornella Bonavita, Ornella Bonavita, Valeria Mollica Poeta, Valeria Mollica Poeta, Massimo Locati, Massimo Locati, Matteo Simonelli, Matteo Simonelli, Raffaella Bonecchi, Raffaella Bonecchi   +12 more
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Angiocentric glioma: the infiltrative glioma with ependymal differentiation [PDF]

Turkish Journal of Pathology, 2013
Angiocentric glioma is an epileptogenic, infiltrative, low grade glial tumor, with ependymal and astrocytic differentiation, most commonly seen in young adults and the pediatric age group. Herein we report a case of 21-year-old male patient who presented with fever and pharmaco-resistant seizures.
Ersen, Ayca, Canda, Tulay, KALEMCİ, ORHAN, MEN, SÜLEYMAN, Yucesoy, Kemal, Canda, M. Serefettin   +5 more
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CHI3L2 Is a Novel Prognostic Biomarker and Correlated With Immune Infiltrates in Gliomas

Frontiers in Oncology, 2021
CHI3L2 (Chitinase-3-Like Protein 2) is a member of chitinase-like proteins (CLPs), which belong to the glycoside hydrolase 18 family. Its homologous gene, CHI3L1, has been extensively studied in various tumors and has been shown to be related to immune ...
Liling Liu, Liling Liu, Yuanzhong Yang, Yuanzhong Yang, Hao Duan, Hao Duan, Jiahua He, Jiahua He, Lu Sun, Lu Sun, Wanming Hu, Wanming Hu, Jing Zeng, Jing Zeng   +13 more
doaj   +1 more source

Transcriptomic and connectomic correlates of differential spatial patterning among gliomas. [PDF]

, 2023
Unravelling the complex events driving grade-specific spatial distribution of brain tumour occurrence requires rich datasets from both healthy individuals and patients.
Suckling, J, Suckling, John, Romero-Garcia, R, Crespo-Facorro, B, Bethlehem, Richard A. I., Crespo-Facorro, Benedicto, Mandal, Ayan, Romero García, Rafael, Bethlehem, RAI, Hart, Michael G., Mandal, AS, Hart, MG   +11 more
core   +1 more source

ADAMDEC1 accelerates GBM progression via activation of the MMP2-related pathway

Frontiers in Oncology, 2022
The ADAM (a disintegrin and metalloprotease) gene-related family including ADAM, ADAMTS, and ADAM-like decysin-1 has been reported to play an important role in the pathogenesis of multiple diseases, including cancers (lung cancer, gliomas, colorectal ...
Huimin Qi, Ping Wang, Hongliang Sun, Xiaohan Li, Xinwei Hao, Wenxiu Tian, Wenxiu Tian, Liting Yu, Jiajian Tang, Junhong Dong, Hongmei Wang, Hongmei Wang   +11 more
doaj   +1 more source

Morphological Patterns of Intracranial Lesions in a Tertiary Care Hospital in North Karnataka: A Clinicopathological and Immunohistochemical Study [PDF]

Journal of Clinical and Diagnostic Research, 2016
Introduction: An “Intra-cranial space occupying lesion” (ICSOL) is defined as a mass lesion in the cranial cavity with a diverse aetiology like benign or malignant neoplasm, inflammatory or parasitic lesion, haematoma, or arterio-venous malformation.
HEMA NEELAKANTAIAH ANADURE, RAMDURG SHASHANK RAVINDRA, ANDOLA SAINATH KARNAPPA   +2 more
doaj   +1 more source

Real-time quantitative polymerase chain reaction assay for detecting 1p and 19q codeletion in glioma

Biomedical and Biotechnology Research Journal, 2023
Background: Glioma is a type of tumor that occurs in the brain and spinal cord. Gliomas begin in the gluey supportive cells (glial cells) that surround nerve cells and help them function.
Niem Van Thanh Vo, Diem Dinh-Kieu Truong, Phan Thi Xinh, Hoang Anh Vu   +3 more
doaj   +1 more source