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Brainstem Gliomas

Neurosurgery Clinics of North America, 1992
Brainstem gliomas, a relatively common form of childhood brain tumor, are highly resistant to therapy. With computed tomography and magnetic resonance imaging, these lesions can be diagnosed with a high degree of reliability. The indications for surgery are unclear. Focal lesions may be amenable to partial resections.
R J, Packer   +3 more
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Nasal Glioma

Archives of Otolaryngology - Head and Neck Surgery, 1981
An 11-month-old girl had a congenital extracranial frontonasal glioma. The tumor was attached to the left membranous septum and excised by a simple ellipse and stalk dissection. The tumor is considered to arise from ectopic neuroectodermal tissue projected through the foramen cecum into the developing nasofrontal cranium and sequestered there on ...
S R, Whitaker, P M, Sprinkle, S M, Chou
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Glioma

Nature Reviews Disease Primers
Gliomas are primary brain tumours that are thought to develop from neural stem or progenitor cells that carry tumour-initiating genetic alterations. Based on microscopic appearance and molecular characteristics, they are classified according to the WHO classification of central nervous system (CNS) tumours and graded into CNS WHO grades 1-4 from a low ...
Weller, Michael   +6 more
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Familial Gliomas

min - Minimally Invasive Neurosurgery, 1979
The authors report two pairs of siblings who had intracranial malignant gliomas. Genetic influences in the occurence of gliomas are discussed.
N, de Tribolet, J P, Deruaz, E, Zander
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Benign Glioma

2023
Benign glioma broadly refers to a heterogeneous group of slow-growing glial tumors with low proliferative rates and a more indolent clinical course. These tumors may also be described as "low-grade" glioma (LGG) and are classified as WHO grade I or II lesions according to the Classification of Tumors of the Central Nervous System (CNS) (Louis et al. in
Peter B, Wu   +3 more
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Epidemiology of Gliomas

2014
Gliomas are the most common type of primary intracranial tumors. Some glioma subtypes cause significant mortality and morbidity that are disproportionate to their relatively rare incidence. A very small proportion of glioma cases can be attributed to inherited genetic disorders.
Quinn T, Ostrom   +4 more
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Gliomas

2013
Gliomas are thought to arise from the glial cells of brain tissue. The spectrum of tumours varies with age, implying that cells in a particular state of development are a prerequisite for the occurrence of some tumour types. Premalignant states are not recognized, so we know little about the earliest events in oncogenesis.
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Chemoresistance in gliomas

Molecular and Cellular Biochemistry, 2008
Despite improved knowledge and advanced treatments of gliomas, the overall survival rate for glioma patients remains low. Gliomas comprise of significant cell heterogeneity that contains a large number of multidrug resistant (MDR) phenotypes and cancer stem cells (CSCs), a combination that may contribute to the resistance to treatment.
Chen, Lu, Amal, Shervington
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AUTOTRANSPLANTATION OF GLIOMAS

Journal of Neuropathology and Experimental Neurology, 1964
1. Five patients with glioblastoma had minced tumor cells injected into the subcutaneous tissues of the thigh or abdomen, and, in two instances, a suspension of normal brain tissue was injected into a comparable site. 2. In the two instances in which normal brain cells were injected, no evidence of their survival or growth could be found. 3.
M G, MITTS, A E, WALKER
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Pediatric Gliomas

2009
Pediatric gliomas comprise a clinically, histologically, and molecularly very heterogeneous group of CNS tumors. In addition, these tumors are largely different from their counterparts occurring in adults, although they are histologically indistinguishable and uniformly classified by the current WHO classification for CNS tumors. Pilocytic astrocytoma (
Stefan, Pfister, Olaf, Witt
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