Results 51 to 60 of about 127,720 (302)
Multi-Task Learning for Small Brain Tumor Segmentation from MRI
Applied Sciences, 2020 Segmenting brain tumors accurately and reliably is an essential part of cancer diagnosis and treatment planning. Brain tumor segmentation of glioma patients is a challenging task because of the wide variety of tumor sizes, shapes, positions, scanning ...
Duc-Ky Ngo +4 more
doaj +1 more source
The use of conventional and advanced magnetic resonance techniques in the assessment of primary brain tumours [PDF]
, 2008 The aim of the work described in this thesis was to investigate the value of conventional, perfusion- and diffusion-weighted magnetic resonance imaging (MRI) in patients with histology-proven low-grade gliomas (LGG), and the potential role of these ...
Caseiras, G.D.B.
core
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Frontiers in Genetics, 2019 Gliomas represent 80% of malignant brain tumors. Because of the high heterogeneity, the oncogenic mechanisms in gliomas are still unclear. In this study, we developed a new approach to identify dysregulated competitive endogenous RNA (ceRNA) interactions
Jinyuan Xu +10 more
doaj +1 more source
A novel 25-ferroptosis-related gene signature for the prognosis of gliomas
Frontiers in Oncology, 2023 BackgroundFerroptosis is closely associated with cancer and is of great importance in the immune evasion of cancer. However, the relationship between ferroptosis and glioma is unclear.MethodsWe downloaded the expression profiles and clinical data of ...
Xiaojiang Peng +7 more
doaj +1 more source
Stem cells and the origin of gliomas: A historical reappraisal with molecular advancements [PDF]
, 2008 Michael L Levy1, Allen L Ho1,2, Samuel Hughes3, Jayant Menon1, Rahul Jandial41Division of Neurosurgery, University of California, San Diego, La Jolla, California, USA; 2Del E Webb Neurosciences, Aging and Stem Cell Research Center, The Burnham Institute ...
Samuel Hughes +9 more
core +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Molecular Therapy: Nucleic Acids, 2018 Circular RNAs (circRNAs) are a type of endogenous non-coding RNAs, which have been considered to mediate diverse tumorigenesis including angiogenesis.
Qianru He +11 more
doaj +1 more source
Spinal cord tumor in a patient with multiple sclerosis: case report [PDF]
Arquivos de Neuro-Psiquiatria, 2002 The association between multiple (MS) sclerosis and cerebral gliomas has been sporadically reported in the literature, causing a long lasting discussion if these lesions occur coincidentally or if MS plaques may actually lead to the genesis of gliomas ...
Mario Augusto Taricco +3 more
doaj +1 more source