Results 31 to 40 of about 122,644 (307)

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Cambio de cobertura y uso de suelo en cuencas tropicales costeras del Pacifico central mexicano

open access: yesInvestigaciones Geográficas, 2017
En los últimos años los humedales costeros de Jalisco han sufrido transformaciones en las confluencias y en las cuencas a las que están asociados. El esquema de la gestión costera sugiere incluir la zona de estudio y las áreas adyacentes en un mismo ...
Alejandro Jalmacin Nené Preciado   +3 more
doaj   +1 more source

Management of granulomatous lobular mastitis: an international multidisciplinary consensus (2021 edition)

open access: yesMilitary Medical Research, 2022
Granulomatous lobular mastitis (GLM) is a rare and chronic benign inflammatory disease of the breast. Difficulties exist in the management of GLM for many front-line surgeons and medical specialists who care for patients with inflammatory disorders of ...
Qian-Qian Yuan   +65 more
doaj   +1 more source

Evaluating the Performance of the Generalized Linear Model (glm) R Package Using Single-Cell RNA-Sequencing Data

open access: yesApplied Sciences, 2023
The glm R package is commonly used for generalized linear modeling. In this paper, we evaluate the ability of the glm package to predict binomial outcomes using logistic regression.
Omar Alaqeeli, Raad Alturki
doaj   +1 more source

[18F]Fluorodeprenyl‐D2 PET as a Tool to Monitor Disease Activity in GAD65‐Ab Autoimmune Encephalitis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate [18F]fluorodeprenyl‐D2 ([18F]F‐DED) positron‐emission tomography (PET) imaging as a biomarker of disease activity in autoimmune encephalitis (AIE) associated with glutamic acid decarboxylase 65 (GAD65) antibodies. Methods [18F]F‐DED PET was performed in 25 GAD65‐AIE patients and 8 controls using dynamic (0–60 min) and ...
Julia S. Dorneich   +19 more
wiley   +1 more source

Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani   +10 more
wiley   +1 more source

The East Atlantic and Mediterranean bluefin tuna stock management: uncertainties and alternatives

open access: yesScientia Marina, 2003
Although the Atlantic bluefin tuna has been studied for more than a century, the assessment of the East stock is characterised by a large amount of uncertainty.
Jean-Marc Fromentin
doaj   +1 more source

Mechanism and Distribution of glmS Ribozymes [PDF]

open access: yes, 2012
Among the nine classes of ribozymes that have been experimentally validated to date is the metabolite-responsive self-cleaving ribozyme called glmS. This RNA is almost exclusively located in the 5'-untranslated region of bacterial mRNAs that code for the production of GlmS proteins, which catalyze the synthesis of the aminosugar glucosamine-6-phosphate
Phillip J, McCown   +2 more
openaire   +2 more sources

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

Birds of a feather (might not) flock together: Exploring the complex interplay of motivation, autonomy and positive emotions in predicting anxiety levels in Hungarian secondary school language learners

open access: yesStudies in Second Language Learning and Teaching
Due to its importance in second/foreign language (L2) learning, anxiety appears to be one of the most important individual differences (IDs). Still, learners’ experiences of anxiety tend to vary considerably, so we set out to investigate the anxiety ...
Ágnes Albert, Kata Csizér
doaj   +1 more source

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