Results 41 to 50 of about 1,355,686 (263)

Communication and Relational Ties in Inter-Professional Teams in Norwegian Specialized Health Care: A Multicentre Study of Relational Coordination

International Journal of Integrated Care, 2018
Introduction: The delivery of integrated care depends on the quality of communication and relationships among health-care professionals in inter-professional teams.
Merethe Hustoft, Øystein Hetlevik, Jörg Aßmus, Sverre Størkson, Sturla Gjesdal, Eva Biringer   +5 more
doaj   +1 more source

Surgical referrals in Northern Tanzania: a prospective assessment of rates, preventability, reasons and patterns

BMC Health Services Research, 2020
Background An effective referral system is essential for a high-quality health system that provides safe surgical care while optimizing patient outcomes and ensuring efficiency.
Desmond T. Jumbam, Gopal Menon, Tenzing N. Lama, William Lodge II, Sarah Maongezi, Ntuli A. Kapologwe, Isabelle Citron, David Barash, John Varallo, Erin Barringer, Monica Cainer, Mpoki Ulisubisya, Shehnaz Alidina, Boniface Nguhuni   +13 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Yarning about fall prevention: community consultation to discuss falls and appropriate approaches to fall prevention with older Aboriginal and Torres Strait Islander people

BMC Public Health, 2017
Background Fall related injury is an emerging issue for older Indigenous people worldwide, yet few targeted fall prevention programs are currently available for Indigenous populations.
Caroline Lukaszyk, Julieann Coombes, Norma Jean Turner, Elizabeth Hillmann, Lisa Keay, Anne Tiedemann, Cathie Sherrington, Rebecca Ivers   +7 more
doaj   +1 more source

Research capacity, motivators and barriers to conducting research among healthcare providers in Tanzania’s public health system: a mixed methods study

Human Resources for Health, 2023
Background Building health research capacity in low- and middle-income countries is essential to achieving universal access to safe, high-quality healthcare.
James T. Kengia, Albino Kalolo, David Barash, Cindy Chwa, Tuna Cem Hayirli, Ntuli A. Kapologwe, Ally Kinyaga, John G. Meara, Steven J. Staffa, Noor Zanial, Shehnaz Alidina   +10 more
doaj   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Can Microfluidics Improve Sperm Quality? A Prospective Functional Study

Biomedicines
The same sperm selection techniques in assisted reproduction clinics have remained largely unchanged despite their weaknesses. Recently, microfluidic devices have emerged as a novel methodology that facilitates the sperm selection process with promising ...
Fernando Meseguer, Carla Giménez Rodríguez, Rocío Rivera Egea, Laura Carrión Sisternas, Jose A. Remohí, Marcos Meseguer   +5 more
doaj   +1 more source