Results 91 to 100 of about 4,491,703 (310)
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Frontiers in Cardiovascular MedicineObjectivesPediatric pulmonary arterial hypertension (PAH) is a severe and potentially fatal disease; however, the global epidemiological burden of pediatric PAH has not been comprehensively elucidated.Study designThe Global Burden of Diseases Study 2021 ...
Ying Chen +8 more
doaj +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Editorial: Globalization of The Journal of Chiropractic Eduction [PDF]
, 2007 Bart N. Green
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Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
MP11-11 ANALYSIS OF GLOBAL EVALUATIVE ASSESSMENT OF ROBOTIC SURGERY (GEARS) AS AN IMMEDIATE ASSESSMENT TOOL IN ROBOTIC SURGERY CURRICULUM [PDF]
, 2016 Jamal Nabhani +4 more
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Global-Supervised Contrastive Loss and View-Aware-Based Post-Processing for Vehicle Re-Identification [PDF]
, 2022 Zhijun Hu +6 more
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Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
, 2018 In recent years historians in many different parts of the world have sought to transnationalize and globalize their perspectives on the past. Despite all these efforts to gain new global historical visions, however, the debates surrounding this movement have remained rather provincial in scope.
Beckert, Sven, Sachsenmaier, Dominic
openaire +3 more sources