Results 111 to 120 of about 16,067,535 (312)

Overview of the Global Sanitation Problem [PDF]

open access: yes
human development, water ...
David Satterthwaite and Gordon McGranahan
core  

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Human Poverty in Transition Economies: Regional Overview for HDR 1997 [PDF]

open access: yes
human development, poverty ...
Ewa Ruminska-Zimny
core  

Pragmatic Content in Global and Local ELT Textbooks [PDF]

open access: gold, 2015
Hussein Meihami, Mobin Khanlarzadeh
openalex   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

The future of the International Health Regulations

open access: yesThe Lancet Global Health, 2022
The Lancet Global Health
doaj   +1 more source

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