Results 151 to 160 of about 18,530,294 (403)
Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance
Molecular Oncology, EarlyView.Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...Hendrika A. Segeren, Kathryn A. Wierenga, Frank M. Riemers, Elsbeth A. van Liere, Bart Westendorp +4 morewiley +1 more sourceClassification of acute myeloid leukemia based on multi‐omics and prognosis prediction value
Molecular Oncology, EarlyView.The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.Yang Song, Zhe Wang, Guangji Zhang, Jiangxue Hou, Kaiqi Liu, Shuning Wei, Yan Li, Chunlin Zhou, Dong Lin, Min Wang, Hui Wei, Jianxiang Wang, Tao Cheng, Yingchang Mi +13 morewiley +1 more sourceAdverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer
Molecular Oncology, EarlyView.We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...Marina N. Sharifi, Eric Feng, Nicholas R. Rydzewski, Amy K. Taylor, Jamie M. Sperger, Yue Shi, Kyle T. Helzer, Matthew L. Bootsma, Viridiana Carreno, Alex H. Chang, Luke A. Nunamaker, Grace C. Blitzer, Tianfu Andy Shang, Aishwarya Subramanian, Anders Bjartell, Andreas Josefsson, Pernilla Wikström, Emily Feng, Manish Kohli, Rendong Yang, Scott M. Dehm, Eric J. Small, Rahul Aggarwal, David A. Quigley, Joshua M. Lang, Shuang G. Zhao, Martin Sjöström +26 morewiley +1 more sourceGlobal, regional, and national burden of stroke and its risk factors, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019
Lancet Neurology, 2021 Valery L Benjamin A Catherine Owens Gregory A Catherine G Feigin Stark Johnson Roth Bisignano Abady Abbasifa, Valery L. Feigin, Benjamin A. Stark, C. Johnson, Gregory A. Roth, C. Bisignano, Gdiom Gebreheat Abady, M. Abbasifard, M. Abbasi-Kangevari, F. Abd-Allah, Vida Abedi, Ahmed Abualhasan, Niveen M. E. Abu-Rmeileh, A. Abushouk, O. Adebayo, Gina Agarwal, P. Agasthi, B. Ahinkorah, Sohail Ahmad, Sepideh Ahmadi, Yusra Ahmed Salih, Budi Aji, S. Akbarpour, R. Akinyemi, Hanadi Al Hamad, Fares Alahdab, S. M. Alif, V. Alipour, S. Aljunid, Sami A. Almustanyir, Rajaa Al-Raddadi, R. Al‐Shahi Salman, N. Alvis-Guzmán, R. Ancuceanu, Deanna Anderlini, Jason A Anderson, A. Ansar, I. Antonazzo, J. Arabloo, J. Ärnlöv, K. D. Artanti, Z. Aryan, S. Asgari, T. Ashraf, Mohammad Athar, A. Atreya, M. Ausloos, A. Baig, Ovidiu Constantin Baltatu, Maciej Banach, Miguel A Barboza, S. Barker-Collo, T. Bärnighausen, M. Barone, Sanjay Basu, Gholamreza Bazmandegan, Ettore Beghi, Mahya Beheshti, Yannick Béjot, A. Bell, Derrick A. Bennett, I. Benseñor, Woldesellassie M. Bezabhe, Y. Bezabih, A. Bhagavathula, Pankaj Bhardwaj, Krittika Bhattacharyya, A. Bijani, B. Bikbov, M. M. Birhanu, A. Boloor, A. Bonny, Michael Brauer, H. Brenner, Dana Bryazka, Z. Butt, F. L. Caetano dos Santos, Ismael Campos-Nonato, C. Cantú-Brito, J. Carrero, C. Castañeda-Orjuela, A. Catapano, P. Chakraborty, J. Charan, Sonali G. Choudhari, E. Chowdhury, D. Chu, Sheng-Chia Chung, David Colozza, V. M. Costa, Simona Costanzo, M. Criqui, O. Dadras, Baye Dagnew, X. Dai, Koustuv Dalal, Albertino Damasceno, Emanuele D'Amico, L. Dandona, R. Dandona, Jiregna Darega Gela, K. Davletov, Vanessa De la Cruz-Góngora, Rupak Desai, Deepak Dhamnetiya, S. Dharmaratne, M. Dhimal, M. Dhimal, Daniel Diaz, M. Dichgans, K. Dokova, R. Doshi, Abdel Douiri, B. B. Duncan, S. Eftekharzadeh, Michael Ekholuenetale, Nevine M. El Nahas, I. Elgendy, Muhammed Elhadi, S. El-Jaafary, Matthias Endres, A. Endries, D. Erku, E. J. Faraon, Umar Farooque, F. Farzadfar, A. Feroze, I. Filip, Florian Fischer, David Flood, Mohamed M Gad, Shilpa Gaidhane, Reza Ghanei Gheshlagh, A. Ghashghaee, N. Ghith, Ghozali Ghozali, S. Ghozy, A. Gialluisi, Simona Giampaoli, S. Gilani, P. Gill, E. Gnedovskaya, Mahaveer Golechha, A. Goulart, Yuming Guo, R. Gupta, Veera Gupta, V. Gupta, P. Gyanwali, N. Hafezi-Nejad, S. Hamidi, Asif Hanif, Graeme J. Hankey, Arief Hargono, Abdiwahab Hashi, Treska S. Hassan, H. Y. Hassen, Rasmus J Havmoeller, Simon Iain Hay, K. Hayat, M. Hegazy, C. Herteliu, R. Holla, S. Hostiuc, Mowafa J Househ, Junjie. Huang, A. Humayun, Bing-Fang Hwang, L. Iacoviello, Ivo Iavicoli, S. E. Ibitoye, O S Ilesanmi, Irena M. Ilic, Milena D. Ilic, Usman Iqbal, S. Irvani, Sheikh Mohammed Shariful Islam, N. Ismail, Hiroyasu Iso, Gaetano Isola, Masao Iwagami, Louis Jacob, Vardhmaan Jain, S. Jang, Sathish Kumar Jayapal, S. Jayaram, R. Jayawardena, P. Jeemon, R. P. Jha, Walter D Johnson, J. Jonas, Nitin Joseph, J. Jozwiak, Mikk Jürisson, Rizwan Kalani, R. Kalhor, Y. Kalkonde, Ashwin Kamath, Z. Kamiab, T. Kanchan, Himal Kandel, André Karch, P. Katoto, G. Kayode, P. Keshavarz, Yousef S. Khader, E. Khan, Imteyaz A Khan, Maseer Khan, Moien A. B. Khan, M. Khatib, J. Khubchandani, Gyu Ri Kim, Min Seo Kim, Y. Kim, A. Kisa, S. Kisa, Mika Kivimäki, D. Kolte, A. Koolivand, S. L. Koulmane Laxminarayana, Ai Koyanagi, K. Krishan, V. Krishnamoorthy, R. Krishnamurthi, G. Kumar, Dian Kusuma, C. La Vecchia, Ben Lacey, H. Lak, T. Lallukka, Savita Lasrado, P. Lavados, Matilde Leonardi, Bingyu Li, Shanshan Li, Hualiang Lin, R. Lin, Xuefeng Liu, Warren D. Lo, S. Lorkowski, G. Lucchetti, Ricardo Lutzky Saute, H. Magdy Abd El Razek, F. Magnani, P. B. Mahajan, Azeem Majeed, Alaa Makki, R. Malekzadeh, A. A. Malik, N. Manafi, M. Mansournia, L. Mantovani, Santi Martini, G. Mazzaglia, M. Mehndiratta, Ritesh G. Menezes, A. Meretoja, Amanual Getnet Mersha, Junmei Miao Jonasson, Bartosz Miazgowski, T. Miazgowski, I. Michalek, E. Mirrakhimov, Y. Mohammad, A. Mohammadian-Hafshejani, S. Mohammed, A. Mokdad, Y. Mokhayeri, M. Molokhia, M. A. Moni, A. Montasir, R. Moradzadeh, L. Morawska, J. Morze, Walter Muruet, K. I. Musa, Ahamarshan Jayaraman Nagarajan, M. Naghavi, S. Narasimha Swamy, B. R. Nascimento, R. Negoi, Sandhya Neupane Kandel, T. H. Nguyen, B. Norrving, Jean Jacques Noubiap, V. Nwatah, Bogdan Oancea, O. Odukoya, A. Olagunju, H. Orru, M. Owolabi, J. Padubidri, A. Pana, Tarang Parekh, Eun-Cheol Park, Fatemeh Pashazadeh Kan, Mona Pathak, M. F. Peres, Arokiasamy Perianayagam, Truong-Minh Pham, M. Piradov, Vivek Podder, S. Polinder, Maarten J. Postma, A. Pourshams, A. Radfar, A. Rafiei, A. Raggi, F. Rahim, V. Rahimi-Movaghar, Mosiur Rahman, Muhammad Aziz Rahman, A. Rahmani, Nazanin Rajai, P. Ranasinghe, C. Rao, Sowmya J. Rao, P. Rathi, D. Rawaf, S. Rawaf, M. Reitsma, V. Renjith, Andre M. N. Renzaho, A. Rezapour, J. A. B. Rodriguez, L. Roever, M. Romoli, Andrzej Rynkiewicz, Simona Sacco, M. Sadeghi, Sahar Saeedi Moghaddam, A. Sahebkar, KM Saif-Ur-Rahman, Rehab Salah, Mehrnoosh Samaei, A. Samy, I. Santos, Milena M. Santric-Milicevic, N. Sarrafzadegan, B. Sathian, D. Sattin, S. Schiavolin, M. Schlaich, M.I. Schmidt, A. Schutte, S. Sepanlou, Allen Seylani, F. Sha, S. Shahabi, M. Shaikh, Mohammed Shannawaz, M. S. R. Shawon, Aziz Sheikh, S. Sheikhbahaei, Kenji Shibuya, Soraya Siabani, D. A. S. Silva, Jasvinder A. Singh, Jitendra Kumar Singh, V. Skryabin, A. Skryabina, B. Sobaih, Stefan Stortecky, S. Stranges, Eyayou Girma Tadesse, Ingan Ukur Tarigan, M. Temsah, Y. Teuschl, A. Thrift, Marcello Tonelli, M. Tovani-Palone, Bach Xuan Tran, Manjari Tripathi, Gebiyaw Wudie Tsegaye, Anayat Ullah, B. Unim, B. Unnikrishnan, Alireza Vakilian, Sahel Valadan Tahbaz, T. Vasankari, N. Venketasubramanian, D. Vervoort, Bay Vo, V. Volovici, K. Vosoughi, G. Vu, L. G. Vu, Hatem A. Wafa, Yasir Waheed, Yanzhong Wang, T. Wijeratne, Andrea S. Winkler, Charles D A Wolfe, Mark Woodward, Jason H Wu, Sarah Wulf Hanson, Xiaoyue Xu, Lalit Yadav, A. Yadollahpour, Seyed Hossein Yahyazadeh Jabbari, Kazumasa Yamagishi, H. Yatsuya, N. Yonemoto, Chuanhua Yu, Ismaeel Yunusa, M. Zaman, S. Zaman, M. Zamanian, R. Zand, A. Zandifar, M. Zastrozhin, Anasthasia Zastrozhina, Yunquan Zhang, Zhi-Jiang Zhang, Chenwen Zhong, Yves Miel H Zuniga, C. Murray +417 moresemanticscholar +1 more sourceTranscriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM
Molecular Oncology, EarlyView.CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.Julia Latowska‐Łysiak, Żaneta Zarębska, Marcin P. Sajek, Adriana Grabowska, Alessia Buratin, Paweł Głodowicz, Julia O. Misiorek, Konrad Kuczyński, Stefania Bortoluzzi, Marek Żywicki, Jan G. Kosiński, Agnieszka Rybak‐Wolf, Rafał Piestrzeniewicz, Anna M. Barciszewska, Katarzyna Rolle +14 morewiley +1 more source
