Results 21 to 30 of about 4,491,703 (310)
ABSTRACT Purpose Chemoimmunotherapy with irinotecan, temozolomide, and dinutuximab (I/T/DIN) has emerged as first‐line therapy for relapsed/refractory (r/r) high‐risk neuroblastoma (HRNB) in North America. Topotecan and cyclophosphamide (T/C) are often used in combination with dinutuximab in the setting of lack of response, progression, or incomplete ...
Benjamin J. Lerman +17 more
wiley +1 more source
Clinical Course and Impact of Breaks in Therapy for Children With Relapsed/Refractory Solid Tumors
ABSTRACT Introduction Pediatric relapsed or refractory (R/R) solid tumors carry a dismal prognosis, and postrelapse patient experiences are not well described. We present postrelapse outcomes, including number of R/R events and subsequent therapy regimens.
Matthew T. McEvoy +5 more
wiley +1 more source
ABSTRACT Hemoglobinopathies are prevalent globally; diagnosis is complex in high genetic admixture populations like Brazil. We report, in two pediatric siblings, the first documented cases in Brazil of heterozygosity for hemoglobin (Hb) O‐Arab with coinheritance of α‐thalassemia (αα/−α4.2; −α3.7/−α4.2), resulting in microcytic and hypochromic anemia ...
Elisângela de Souza Miranda Muynarsk +9 more
wiley +1 more source
Introduction: There is a general interpretation that the distribution and pattern of various cancers exhibit geographical variations between developed and developing countries.
Jacob Kuruvilla +1 more
doaj +1 more source
Global Challenges, Global Opportunities
Academia is at an exciting crossroads. The global problems we face are immense, but the good news is we know how to address most of them. Our primary challenge today is not a lack of knowledge but a failure to scale up what we already know works. Some of the skills to implement what we know are medical, many are not.
openaire +4 more sources
Teaching and Learning in Industrial Era 4.0
In the Industrial Revolution 4.0, education is a big challenge this century. If we don't change the way we teach, the next 30 years we will experience great difficulties.
Sri Idayatun
doaj +1 more source
ABSTRACT Background Patients with high‐risk neuroblastoma who either are refractory to induction chemotherapy or relapse following multi‐modal treatment have a dismal prognosis. Based on data from the BEACON trial, since 2021 the UK national guidelines recommend bevacizumab, irinotecan, and temozolomide (BIT) for patients with relapsed/refractory ...
Thomas J. Jackson +20 more
wiley +1 more source
Pemberdayaan Masyarakat dan Mahasiswa dalam Pembersihan Pantai Pulau Kabung Selatan
Kabung Island, which is located in the Bengkayang Regency Government area, is one of 226 small islands in West Kalimantan. Busy visits to the island during the school holidays and weekends have resulted in a large distribution of garbage in the waters ...
Anthoni B Aritonang +5 more
doaj +1 more source
arXiv admin note: substantial text overlap with arXiv:1410 ...
Onur Atan +2 more
openaire +4 more sources
ABSTRACT Background Parents of children treated for acute lymphoblastic leukemia (ALL) often experience significant caregiver burden and disruption to their well‐being. While parent quality of life (QoL) during treatment is well characterized, little is known about outcomes during early survivorship.
Sara Dal Pra +3 more
wiley +1 more source

