Results 21 to 30 of about 15,262,784 (310)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács   +8 more
wiley   +1 more source

A Call to Action: An Open Letter From Global Health Professionals. Signed By Over 3000 Global Health Professionals

open access: yesSocial Medicine, 2023
The world is alight with horror, grief, and rage. In the last 34 days, we witnessed the mass killing of civilians and numerous violations of international law. The October 7 Hamas-led attacks on Israel resulted in the deaths of 1400 Israelis. Since then,
Global Health Professionals
doaj  

Global citizens [PDF]

open access: yesBritish Journal of Nursing, 2019
Nurses and nursing students from the UK and overseas are learning in each other's countries
Porteous, Debbie   +6 more
openaire   +2 more sources

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait   +23 more
wiley   +1 more source

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski   +9 more
wiley   +1 more source

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul   +13 more
wiley   +1 more source

Distribution pattern and its correlation for oral cancer rate and human development rank for countries: An ecological approach

open access: yesContemporary Clinical Dentistry, 2021
Introduction: There is a general interpretation that the distribution and pattern of various cancers exhibit geographical variations between developed and developing countries.
Jacob Kuruvilla   +1 more
doaj   +1 more source

Global Challenges, Global Opportunities

open access: yesAnnals of Global Health, 2014
Academia is at an exciting crossroads. The global problems we face are immense, but the good news is we know how to address most of them. Our primary challenge today is not a lack of knowledge but a failure to scale up what we already know works. Some of the skills to implement what we know are medical, many are not.
openaire   +4 more sources

Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle   +5 more
wiley   +1 more source

Teaching and Learning in Industrial Era 4.0

open access: yesIbriez: Jurnal Kependidikan Dasar Islam Berbasis Sains, 2020
In the Industrial Revolution 4.0, education is a big challenge this century. If we don't change the way we teach, the next 30 years we will experience great difficulties.
Sri Idayatun
doaj   +1 more source

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