Results 111 to 120 of about 1,478,682 (342)

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Making global knowledge accessible to EFL speakers of an undergraduate leadership program through a flipped and ubiquitous learning environment

Technology in Language Teaching & Learning, 2019
This paper reports on how an undergraduate global leadership course was designed and implemented at a Japanese mid-sized private university to match the Japanese government’s initiative of fostering global individuals through education. By incorporating a flipped learning approach (Bergmann & Sam, 2012) and the content materials from a Massive Open
Nobue Tanaka-Ellis, Sachiyo Sekiguchi
openaire   +2 more sources

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Educating Girls: Complexities of Informing Meaningful Social Change

Studies in Social Justice, 2018
Jackie Kirk devoted her career to trying to bridge the relationships among research, policy and practice for the purpose of making the world a better place for children, teachers, and communities. Reflecting her priorities, we examine herein how research,
Karen Monkman
doaj   +1 more source

Advancing Equity and Accessibility: DataCite's Global Access Program

In February 2023, DataCite lauched the Global Access Program (GAP) to improve access and enable communities in lesser-represented regions to further benefit from our open infrastructure services. The program has been made possible in part by grant 2022-316573 from the Chan Zuckerberg Initiative.Mohamad Mostafa has participated in the panel discussion ...
openaire   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Development of the WHO Caregiver Skills Training Program for Developmental Disorders or Delays

Frontiers in Psychiatry, 2019
Globally, 52.9 million children under the age of 5 experience a developmental disability, such as sensory impairment, intellectual disability, and autism spectrum disorders. Of these 95% live in low-and-middle-income countries.
E. Salomone, Laura Pacione, Stephanie Y. Shire, F. Brown, B. Reichow, C. Servili   +5 more
semanticscholar   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Weekly Volcanic Activity Report

, 2003
The Weekly Volcanic Activity Report is a cooperative project between the Global Volcanism Program of the Smithsonian's National Museum of Natural History and the US Geological Survey's Volcano Hazards Program.
Global Volcanism Program
core  

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source