Results 191 to 200 of about 1,478,682 (342)

Happy birthday, dear TSACO: congratulations on the 10-year anniversary of Trauma Surgery & Acute Care Open (TSACO). [PDF]

Trauma Surg Acute Care Open
Haut ER.
europepmc   +1 more source

The Chilean AIDS Cohort: A Model for Evaluating the Impact of an Expanded Access Program to Antiretroviral Therapy in a Middle-Income Country-Organization and Preliminary Results

Journal of Acquired Immune Deficiency Syndromes, 2005
M. Wolff, C. Beltrán, Patricia Vásquez, Marisol Ayala, M. Valenzuela, G. Berríos, A. Arredondo   +6 more
semanticscholar   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

The TB Portals: an Open-Access, Web-Based Platform for Global Drug-Resistant-Tuberculosis Data Sharing and Analysis

Journal of Clinical Microbiology, 2017
A. Rosenthal, A. Gabrielian, Eric Engle, D. Hurt, S. Alexandru, V. Crudu, Eugene Sergueev, V. Kirichenko, V. Lapitskii, E. Snezhko, V. Kovalev, Andrei Astrovko, A. Skrahina, J. Taaffe, Michael A. Harris, Alyssa Long, K. Wollenberg, I. Akhundova, S. Ismayilova, A. Skrahin, E. Mammadbayov, Hagigat Gadirova, R. Abuzarov, M. Seyfaddinova, Z. Avaliani, I. Strâmbu, D. Zaharia, A. Muntean, Eugen Ghita, M. Bogdan, Roxana Mindru, V. Spînu, Alexandra Sora, C. Ene, S. Vashakidze, N. Shubladze, U. Nanava, A. Tuzikov, Michael Tartakovsky   +38 more
semanticscholar   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Community Power and Global Learning: <i>A Case Study of the Four Pillar Model of CORD from India to Michigan</i>. [PDF]

Ann Glob Health
Ramanathan VK, Plum A, Paul N, Babuska K, Pigott M, Metre K.   +5 more
europepmc   +1 more source

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Bridging the Gender Gap in Health Care Innovation: The Evolution of FemTech. [PDF]

J Med Internet Res
Cato JC.
europepmc   +1 more source