Results 91 to 100 of about 1,001,303 (306)

Law–Space Nexus, Global Governance, and Global Administrative Law [PDF]

, 2019
This chapter sheds light on the multinational research project approach to global governance, which is known as global administrative law (GAL), with a focus on the unease GAL has expressed with its own constitutional implications. The argument proceeds as follows.
openaire   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

MALTA: A Zonally Averaged Global Atmospheric Transport Model for Long‐Lived Trace Gases

Journal of Advances in Modeling Earth Systems
We present a two‐dimensional, zonally averaged global model of atmospheric transport named MALTA: Model of Averaged in Longitude Transport in the Atmosphere. It aims to be accessible to a broad community of users, with the primary function of quantifying
Luke M. Western, Scott D. Bachman, Stephen A. Montzka, Matt Rigby   +3 more
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Public Administration in Turkey

, 2018
This work serves as a comprehensive collection of global scholarship regarding the vast fields of public administration and public policy. Written and edited by leading international scholars and practitioners, this exhaustive resource covers all areas ...
Üstüner, Mustafa Yılmaz, Yavuz, Nilay
core  

Transnational administration of regional and global policies

, 2020
Transnational administration is the routinization and bureaucratization of global governance. Concepts of transnational administration move beyond methodological nationalism and absolutist understandings of administrative sovereignty vested solely with ...
Moloney, K., Kim Moloney, Stone, D., Diane Stone   +3 more
core   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Global precipitation climatology

, 2016
This visualziation shows the monthly mean precipitation around the globe from 1979 - 2008. Data was provided by the NOAA Cooperative Institute for Climate Studies at the University of MarylandEducação Superior::Ciências Exatas e da Terra ...
National Oceanic and Atmospheric Administration
core   +1 more source

Anticipated facilitators and barriers for long-acting injectable antiretrovirals as HIV treatment and prevention in Vietnam: a qualitative study among healthcare workers

BMC Infectious Diseases
Background Long-acting injectable antiretrovirals (LAI-ARVs) for HIV prevention and treatment have been demonstrated in clinical trials to be non-inferior to daily oral medications, providing an additional option to help users overcome the challenges of ...
My T. Dang, Yen N. Le, Sarah Naz-McLean, Nhung T. T. Vo, Phuong T. Do, Linh T. T. Doan, Nhan T. Do, Mai T. Nguyen, An H. Phan, Eric J. Dziuban, Ramona Bhatia, Lisa Cosimi, Huong T. T. Phan, Todd M. Pollack   +13 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source