Results 41 to 50 of about 686,198 (267)

Assessing the impact of human activities on ecosystem asset dynamics in the Yellow River Basin from 2001 to 2020

Scientific Reports
The intensification of human activities in the Yellow River Basin has significantly altered its ecosystems, challenging the sustainability of the region’s ecosystem assets.
Lei Ming, Yuandong Wang, Guangxu Liu, Lihong Meng, Xiaojie Chen   +4 more
doaj   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

Funding Strategies of G-SIBs

Problemy Zarządzania, 2021
Purpose: The purpose of the article is to analyze the main features of the identified funding strategies of G-SIBs and changes in strategies under the influence of financial market conditions and new regulatory requirements.
Igor Kravchuk
doaj   +1 more source

Assessing the Value of International Workers:a Case of Shell Petroleum Development Company in Nigeria [PDF]

, 2012
As a result of globalization, many companies, be it corporate, public or international operates on a global scale. With the rise of companies operating in a global village, many companies are also expanding internationally.
Iyiola , O.O., Osibanjo, Adewale Omotayo
core   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Post construction infrastructural adaptation of social practices in Dhaka’s under flyover spaces

npj Urban Sustainability
Transportation infrastructures often impose a rigid and controlled formation over the organic dynamism of urban areas. This blend of infrastructure and urban context redefines transportation systems beyond their purely functional roles, creating ...
Srijon Barua, Hirohide Kobayashi
doaj   +1 more source

GESTIÓN DE RECURSOS INTANGIBLES EN INSTITUCIONES DE EDUCACIÓN SUPERIOR [PDF]

RAE: Revista de Administração de Empresas, 2015
The organizations are developed in challenging and competitive environments, created by demands of societies, and marked by the global financial crisis that extends even to the Institutions of Higher Education (IHEs), which are aimed at meeting the needs
Yilsy María Núñez Guerrero, Carlos Rodríguez Monroy   +1 more
doaj  

The European ETF Market: What can be done better? ECMI Commentary No. 53 / 24 April 2018 [PDF]

, 2018
Growing demand in recent years for low-cost, easily tradeable, liquid and transparent investment products, resulted in the global expansion of the Exchange-Traded Fund (ETF) industry. Since 2007, global assets under management in ETFs skyrocketed from €0.
Thomadakis, Apostolos
core  

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Warming exacerbates global inequality in forest carbon and nitrogen cycles

Nature Communications
Forests are invaluable natural resources that provide essential services to humanity. However, the effects of global warming on forest carbon and nitrogen cycling remain uncertain. Here we project a decrease in total nitrogen input and accumulation by 7 ±
Jinglan Cui, Ouping Deng, Miao Zheng, Xiuming Zhang, Zihao Bian, Naiqing Pan, Hanqin Tian, Jianming Xu, Baojing Gu   +8 more
doaj   +1 more source