Results 141 to 150 of about 5,198,351 (376)
Effectiveness and Safety of Nusinersen and Risdiplam in Spinal Muscular Atrophy: A Systematic Review
ABSTRACT Objective Spinal Muscular Atrophy (SMA) is a rare genetic disorder marked by progressive muscle weakness and mobility loss. It has a profound physical, emotional and social impact on patients and caregivers, requiring comprehensive medical and supportive care.
Amin Mehrabian +9 more
wiley +1 more source
ABSTRACT Objective People with epilepsy (PWE) may experience cognitive deficits but fail to undergo formal evaluation. This study compares cognitive status between PWE and healthy controls in the West African Republic of Guinea. Methods A cross‐sectional, case–control study was conducted in sequential recruitment phases (July 2024–July 2025) at Ignace ...
Maya L. Mastick +14 more
wiley +1 more source
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin +11 more
wiley +1 more source
Global attractor of the extended Fisher-Kolmogorov equation in
The long-time behavior of solution to extended Fisher-Kolmogorov equation is considered in this article. Using an iteration procedure, regularity estimates for the linear semigroups and a classical existence theorem of global attractor, we prove that the
Luo Hong
doaj
Pullback D-Attractor of Coupled Rod Equations with Nonlinear Moving Heat Source
We consider the pullback D-attractor for the nonautonomous nonlinear equations of thermoelastic coupled rod with a nonlinear moving heat source. By Galerkin method, the existence and uniqueness of global solutions are proved under homogeneous boundary ...
Danxia Wang, Jianwen Zhang, Yinzhu Wang
doaj +1 more source
Objective This study aimed to evaluate the impact of a series of policies that mandated switching patients with inflammatory arthritis (IA) from an originator biologic to a biosimilar in British Columbia, Canada, on health care resource use and cost.
HaoHung Dang +4 more
wiley +1 more source
Exponential attractors for a Cahn-Hilliard model in bounded domains with permeable walls
In a previous article [7], we proposed a model of phase separation in a binary mixture confined to a bounded region which may be contained within porous walls. The boundary conditions were derived from a mass conservation law and variational methods.
Ciprian G. Gal
doaj
Objective This study examined the global and regional temporal changes in cross‐country inequalities of site‐specific osteoarthritis (OA) burden from 1990 to 2021. Methods Age‐standardized years lived with disability rates (ASYRs) for site‐specific OA across 204 countries and territories were obtained from the Global Burden of Diseases, Injuries, and ...
Haowei Chen +14 more
wiley +1 more source

