Results 101 to 110 of about 21,597 (261)

Uncoupling Type I Interferon Benefits From Inflammatory Toxicity: Transformer‐Prioritized Precision Agonists for Potent and Safer Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
A Transformer‐based AI framework, DLINP, screens millions of compounds to identify Co68, a cobalt‐pincer organometallic complex that biases TLR4‐MD2 signaling toward antitumor interferon activation while suppressing inflammatory toxicity through an early TLR4‐SYK‐STAT1 axis.
Xuefei Guo   +10 more
wiley   +1 more source

Global dynamics of a modified hybrid Van der Pol-Rayleigh oscillator II

open access: yesElectronic Journal of Differential Equations
In this article, we study a modified hybrid Van der Pol-Rayleigh oscillator. We consider bifurcation diagrams and global phase portraits in the Poincare disc under some restrictions on the parameters.
Yuhuan Lu, Rui Zhang
doaj  

Fundamental Challenges, Physical Implementations, and Integration Strategies for Ising Machines in Large‐Scale Optimization Tasks

open access: yesAdvanced Electronic Materials, EarlyView.
Ising machines are emerging as specialized hardware solvers for computationally hard optimization problems. This review examines five major platforms—digital CMOS, analog CMOS, emerging devices, coherent optics, and quantum systems—highlighting physics‐rooted advantages and shared bottlenecks in scalability and connectivity.
Hyunjun Lee, Joon Pyo Kim, Sanghyeon Kim
wiley   +1 more source

Exceptional Antimodes in Multi‐Drive Cavity Magnonics

open access: yesAdvanced Electronic Materials, EarlyView.
Driven‐dissipative cavity‐magnonics provides a flexible platform for engineering non‐Hermitian physics such as exceptional points. Here, using a four‐port, three‐mode system with controllable microwave interference, antimodes and coherent perfect extinction (CPE) are realized, enabling active tuning to antimode exceptional points.
Mawgan A. Smith   +4 more
wiley   +1 more source

The Local Bifurcation of Food Chain Prey-Predator Model with Crowley-Martin-Type of Functional Response

open access: yesIbn Al-Haitham Journal for Pure and Applied Sciences
In this work, the conditions of the occurrence of the local bifurcation (such as saddle-node, trans critical ,and pitchfork) of all steady points of a food chain model. With fear and Growly-Martin functional response have been established.
Asmaa Aziz, Azhar Abbas Majeed
doaj   +1 more source

The bifurcations of modern globalization

open access: yesКонтуры глобальных трансформаций: политика, экономика, право, 2016
In the article the influence of the crisis of industrial civilization on the modern political development is analyzed. The phenomenon of ideology and its actual transformations are in the focus of the author’s attention. In the article it’s shown that the ideology of neoliberalism is a reason for the rise of global tension.
openaire   +1 more source

Synchronization of Analog Neuron Circuits With Digital Memristive Synapses: An Hybrid Approach

open access: yesAdvanced Electronic Materials, EarlyView.
An hybrid circuit mimicking neural units coupled using memristive synapses is introduced. The analog neurons provide flexibility and robustness, and the digital memristive coupling guarantees the full reconfigurability of the interconnection. The onset of a synchronized spiking behavior in two circuits mimicking the Izhikevich neuron is discussed from ...
Lamberto Carnazza   +3 more
wiley   +1 more source

Global branching for discontinuous problems involving the p-Laplacian

open access: yesElectronic Journal of Differential Equations, 2013
In this article, we study elliptic problems with discontinuous nonlinearities involving the p-Laplacian both in bounded and unbounded domains. We prove that there exists a global branch of positive solutions under some suitable assumptions of the ...
Guowei Dai, Ruyun Ma
doaj  

Long Noncoding RNAs in Aortic Dissection: Mechanistic Roles and Therapeutic Potential

open access: yesAGING MEDICINE, EarlyView.
Aortic dissection (AD) involves vascular inflammation, VSMC dysfunction, and ECM degradation. LncRNAs regulate AD progression via ceRNA networks, with great potential as diagnostic biomarkers and therapeutic targets, while further clinical validation is needed.
Chao Chang   +5 more
wiley   +1 more source

Global properties and multiple solutions for boundary-value problems of impulsive differential equations

open access: yesElectronic Journal of Differential Equations, 2013
This article presents global properties and existence of multiple solutions for a class of boundary value problems of impulsive differential equations.
Jing Wang, Baoqiang Yan
doaj  

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