Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler +20 more
wiley +1 more source
Global burden of schizophrenia in 204 countries and regions from 1990 to 2021 and machine learning-based projections to 2036: an analysis of the 2021 global burden of disease study. [PDF]
Feng Z, Shan X, Fan B, Yang L, Gong F.
europepmc +1 more source
Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito +14 more
wiley +1 more source
Global burden of dengue from 1990 to 2021: a systematic analysis from the Global Burden of Disease study 2021. [PDF]
Zheng J +7 more
europepmc +1 more source
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang +10 more
wiley +1 more source
Global burden and health inequalities of premature coronary artery disease attributed to high fasting plasma glucose/body mass: insights from the Global Burden of Disease study 2021. [PDF]
Wang H +10 more
europepmc +1 more source
Global burden of epilepsy attributable to neonatal disorders in children from 1990 to 2021. [PDF]
Zhong S +7 more
europepmc +1 more source
The global burden of ischemic heart disease attributable to trans fatty acid in 204 countries and territories, 1990-2023: a systematic analysis for the Global Burden of Disease Study 2023. [PDF]
Wang X, Liang G.
europepmc +1 more source
The global burden of age-related hearing loss among individuals aged 60 years and older: An analysis for the global burden of disease study 2021 and predictions to 2050. [PDF]
Zhou P, Wu H, Xu K, Pan X, Li L.
europepmc +1 more source

