Results 41 to 50 of about 4,759,858 (314)

Organizations for Global Simultaneous New Model Launching

Annals of Business Administrative Science, 2017
Simultaneously launching new models globally becomes a problem with an increase in global production. Although Toyota Motor Corporation and Hyundai Motor Company have different production systems, they have almost at the same time created organizations ...
Youngkyo SUH
doaj   +1 more source

Adjunctive Therapeutic Plasma Exchange in Refractory Adult‐Onset Still's Disease Complicated by Secondary Macrophage Activation Syndrome: A Single‐Center Experience

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Adult‐onset Still's disease (AOSD) complicated by macrophage activation syndrome (MAS) carries substantial mortality. The role of therapeutic plasma exchange (TPE) remains uncertain. Methods We retrospectively analyzed patients with AOSD‐MAS treated with TPE at a single‐center.
Masataka Ueda, Tomohiro Saito, Masahide Mizobuchi, Tomoki Shimomura, Saki Kawamori, Mitsuru Kawanishi, Natsuko Hattori, Jo Sugiyama, Satoshi Tsubata, Hanami Horiguchi, Kazuki Abe, Nao Iida, Yuki Kajio, Nao Oguro, Ryo Yanai, Hirokazu Honda   +15 more
wiley   +1 more source

A case of severe generalized pustular psoriasis successfully treated with IL-17A monoclonal antibody and granulocyte removal therapy

Renal Replacement Therapy, 2022
Background Generalized pustular psoriasis (GPP) usually presents with fever, generalized flushing, and multiple sterile pustules on the skin, which histopathologically form subcorneal pustules characterized by Kogoj spongiform pustules.
Keiki Shimada, Daisuke Katagiri, Aika Kato, Naoto Nunose, Motohiko Sato, Yuri Katayama, Kanako Terakawa, Takahito Niikura, Emi Sakamoto, Yuki Yoshizaki, Minami Suzuki, Takashi Fukaya, Takeshi Tamaki, Hideki Takano   +13 more
doaj   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Fouling behavior of wavy-patterned pore-filling membranes in reverse electrodialysis under natural seawater and sewage effluents

npj Clean Water, 2022
Reverse electrodialysis (RED) generates electricity from a mixture of seawater and river water. Herein, patterned membranes consisting of ultra-thin pore-filling membranes (16-μm thick) were used to determine whether the RED system operates steadily when
Jiyeon Choi, Won-Sik Kim, Han Ki Kim, Seung Cheol Yang, Ji-Hyung Han, Yoon Cheul Jeung, Nam Jo Jeong   +6 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Assessing a partnership-based model of surgical education in the Global South: a mixed methods study of the University of Global Health Equity, Rwanda

BMC Surgery
Background Workforce shortages, resource limitations, and inadequate capacity in African higher education institutions are significant challenges that hinder their global competitiveness in generating knowledge products.
Naol Belema Gemechu, Gatwiri Murithi, Derbew Fikadu Berhe, Betel Amdeslassie Fenta, Amanuel Adane Bitew, Tairu Fofanah, Barnabas Tobi Alayande, Abebe Bekele, Geoffrey Anderson, Robert Riviello   +9 more
doaj   +1 more source

Case report: new development of fibrosing interstitial lung disease triggered by HIV-related pneumocystis pneumonia

BMC Pulmonary Medicine, 2019
Background Fibrosing interstitial lung disease is the poor prognostic non-infectious lung disease by unknown etiology. Here, we present one case developing interstitial pneumonia with fibrosis after treatment of pneumocystis pneumonia (PCP) in newly ...
Tetsuya Suzuki, Yukiko Shimoda, Katsuji Teruya, Hiroyuki Gatanaga, Yoshimi Kikuchi, Shinichi Oka, Koji Watanabe   +6 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Inappropriate use of antibiotics for childhood diarrhea case management — Kenya, 2009–2016

BMC Public Health, 2019
Background Antibiotics are essential to treat for many childhood bacterial infections; however inappropriate antibiotic use contributes to antimicrobial resistance.
Chulwoo Rhee, George Aol, Alice Ouma, Allan Audi, Shadrack Muema, Joshua Auko, Richard Omore, George Odongo, Ryan E. Wiegand, Joel M. Montgomery, Marc-Alain Widdowson, Ciara E. O’Reilly, Godfrey Bigogo, Jennifer R. Verani   +13 more
doaj   +1 more source