Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Rethinking science diplomacy and global biosecurity: challenges, emerging practices and the way forward [PDF]
Suryesh Kumar Namdeo, Joy Yueyue Zhang
openalex +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
COVID-19 & UNESCO GLOBAL GEOPARK KALDERA TOBA: PELUANG DAN TANTANGAN PENGEMBANGAN PARIWISATA BERKELANJUTAN DI KAWASAN DANAU TOBA [COVID-19 & UNESCO GLOBAL GEOPARK TOBA CALDERA: OPPORTUNITIES AND CHALLENGES FOR SUSTAINABLE TOURISM DEVELOPMENT IN LAKE TOBA AREA] [PDF]
, 2021 Karmel Hebron Simatupang +1 more
openalex +1 more source
The global groundwater situation: overview of opportunities and challenges [PDF]
Groundwater offers us few but precious opportunities for alleviating the misery of the poor; but it poses manyԡnd dauntingԣhallenges of preserving the resource itself.
Molden, David J. +3 more
core +1 more source
Diplomacy, Globalization and Heteropolarity: The Challenge of Adaptation
, 2017 Daryl Copeland
openalex +2 more sources
The global credit boom: challenges for macroeconomics and policy [PDF]
The recent financial crisis has put the spotlight on the rapid rise in credit which preceded it. In this paper, we provide an empirical and theoretical analysis of the credit boom and the macroeconomic context in which it developed. We find that the boom
Hume, Michael, Sentance, Andrew
core
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Leveraging a Global Partnership to Address COVID‐19‐Related Mental Health Challenges [PDF]
Vinciya Pandian +17 more
openalex +1 more source