Results 51 to 60 of about 6,720,476 (300)

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski   +9 more
wiley   +1 more source

Systematic review and meta-analysis of ex-post evaluations on the effectiveness of carbon pricing

open access: yesNature Communications
Today, more than 70 carbon pricing schemes have been implemented around the globe, but their contributions to emissions reductions remains a subject of heated debate in science and policy.
Niklas Döbbeling-Hildebrandt   +14 more
doaj   +1 more source

Decentralization and Regionalization of Surgical Care: A Review of Evidence for the Optimal Distribution of Surgical Services in Low- and Middle-Income Countries [PDF]

open access: yesInternational Journal of Health Policy and Management, 2019
Background While recommendations for the optimal distribution of surgical services in high-income countries (HICs) exist, it is unclear how these translate to resource-limited settings.
Katherine R. Iverson   +8 more
doaj   +1 more source

Coastal management: Global change …. global observation?

open access: yes, 1997
The theme of the present discussion is to consider coastal observation needs in the broader context of a sustainable, integrated management response to coastal change. Thus underlining the notion that observations are an element of a more comprehensive process.
Stive, M.J.F. (author)   +2 more
openaire   +4 more sources

HRM, organizational capacity for change, and performance: a global perspective [PDF]

open access: yes, 2012
This special issue brings together a variety of articles, each one enriching understanding about whether and how human resource management (HRM) influences organizational performance (however defined) against a backdrop of complex change.
Antila   +46 more
core   +2 more sources

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul   +13 more
wiley   +1 more source

Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle   +5 more
wiley   +1 more source

global change

open access: yesTellus B, 2011
A major international effort is now underway to understand in quantitative terms the interacting physical, chemical and biological processes that govern the global environment. The contributions of Professor Bert Bolin to this initiative are noted. It is now timely to incorporate the social processes into the triad of natural phenomena that determine ...
  +5 more sources

Methodological aspects of ecosystem service valuation at the national level [PDF]

open access: yesOne Ecosystem, 2018
Ecosystem service valuations focusing on the assessment of ecosystem service values in space and time have recently been receiving considerable attention.
David Vačkář   +3 more
doaj   +2 more sources

Pulmonary Dysfunction Is Associated With Sleep Study Abnormalities in Children With Sickle Cell Disease: A Multicenter Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Pulmonary dysfunction and sleep abnormalities are common in children with sickle cell disease (SCD) and are associated with worse clinical outcomes. Whether spirometry abnormalities are associated with polysomnography (PSG) findings remains unclear.
Ammar Saadoon Alishlash   +4 more
wiley   +1 more source

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