Results 171 to 180 of about 6,364,051 (298)
ABSTRACT Background Right ventricular (RV) to left ventricular (LV) end‐diastolic volume ratio (RV/LV) is a validated marker of RV dilation in pulmonary arterial hypertension (PAH), yet its impact on LV myocardial function and the underlying mediating pathway is incompletely characterized.
Han Fang +11 more
wiley +1 more source
Abstract Gymnema sylvestre (Retz.) R.Br. ex‐Schult., commonly known as “gurmar” or “sugar destroyer,” belongs to the Apocynaceae family and is traditionally used in Ayurveda for diabetes management. This review synthesizes ethnomedicinal evidence with contemporary pharmacological studies, to evaluate the therapeutic properties and mechanistic actions ...
Faiza Saeed +5 more
wiley +1 more source
Proteoforms in Disease: Biomedical Applications of Top‐Down Proteomics
ABSTRACT The proteome is a dynamic landscape of proteoforms arising from genetic mutations, alternative splicing, and post‐translational modifications (PTMs), which collectively drive biological function and disease phenotypes. Mass spectrometry (MS)‐based proteomics has emerged as an essential technique for elucidating this molecular complexity ...
Holden T. Rogers +5 more
wiley +1 more source
Impact of hypertrophic pattern and obstruction on cardiovascular magnetic resonance myocardial strain and left atrioventricular coupling in hypertrophic cardiomyopathy: a retrospective study. [PDF]
Li Y, Li Z, Chen S, Long L.
europepmc +1 more source
Breathe, Eat, Talk: Three Essential Ingredients to Quality‐of‐Life Outcomes in Movement Disorders
Abstract Background Breathing, eating, and talking (BET) impairments are common yet frequently underrecognized features of movement disorders. Deficits in respiration, swallowing, voice, and speech may emerge early in the course of a disease, adversely affecting safety, participation, and quality of life.
John Dean +16 more
wiley +1 more source
Peak Cardiac Mechanical and Haemodynamic Responses During Incremental Exercise Are Temporally Associated With Ventilatory Thresholds: Novel Insight Into the Coordination of Integrative Physiological Responses to Exercise. [PDF]
Spahiu F +5 more
europepmc +1 more source
ABSTRACT Purpose Left ventricular (LV) strain is an early indicator of myocardial dysfunction. However, conventional strain metrics do not fully account for the multidirectional nature of myocardial deformation. The strain rate tensor, derived from velocity‐encoded MRI, represents the time‐resolved magnitude and direction of strain rate without the ...
Lasse Totland +7 more
wiley +1 more source
Multiparametric CMR evaluation of myocardial remodeling in dystrophinopathy. [PDF]
Luo W +9 more
europepmc +1 more source
ABSTRACT Gas generation and migration in bentonite buffer materials are critical processes affecting the performance of deep geological repositories for radioactive waste. This study presents a new hydro‐mechanical formulation for simulating gas migration in saturated, compacted bentonite, with particular emphasis on the role of non‐uniform stress ...
Desmond Talamwin Sunkpal, Mamadou Fall
wiley +1 more source
Multiscale modeling for dynamic installatioin. ABSTRACT The dynamic installation of metal interference bushings has demonstrated significant potential for improving the mechanical performance of carbon fiber‐reinforced polymer (CFRP) joints. However, the underlying mechanisms governing the remaining life enhancement remain insufficiently understood ...
Yingjiang Guo +4 more
wiley +1 more source

