Results 261 to 270 of about 2,243,884 (354)

DISTENDER indicators for Round 1 (only climate signal) and for: Air Quality and Emissions; Urban Heat Island; Health; Water; Energy; Agroforestry; Sectorial economy; Risk and Vulnerability. Case study: The North-east of the Netherlands (HUAS). Global climate model: Ind. Scenario: Ind.

DISTENDER, ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON UOA, UNIVERSIDADE DE AVEIRO, UNIVERSITAT ZU KOLN, CLIMATE SOLUTIONS UNIPESSOAL LDA, UNIVERSIDAD POLITECNICA DE MADRID, UK CENTRE FOR ECOLOGY & HYDROLOGY   +6 more
openalex   +1 more source

Restriction of Individual Branched‐Chain Amino Acids has Distinct Effects on the Development and Progression of Alzheimer's Disease in 3xTg Mice

Advanced Science, EarlyView.
Protein restriction (PR) slows Alzheimer's disease (AD) in mice, and other benefits of PR are due to decreased branched‐chain amino acids (BCAAs). We show that restricting any BCAA has benefits, with sex‐ and BCAA‐specific impacts on pathology, molecular signaling, and cognition.
Reji Babygirija, Cara L. Green, Michelle M. Sonsalla, Izabelle Marie F. Le, Fan Xiao, Sarah Yandell, Mariah F. Calubag, Michaela E. Trautman, Anna Tobon, Ryan Matoska, Chung‐Yang Yeh, Charles I. Opara, Isaac Grunow, Diana Vertein, Sophia Schlorf, Bailey A. Knopf, Michael J. Rigby, David A. Harris, Mark P. Keller, Alan D. Attie, Luigi Puglielli, Cholsoon Jang, Dudley W. Lamming   +22 more
wiley   +1 more source

The heat is on: sensitivity of goldsinny wrasse to global climate change. [PDF]

Conserv Physiol
Perry D, Tamarit E, Morgenroth D, Gräns A, Sturve J, Gullström M, Thor P, Wennhage H.   +7 more
europepmc   +1 more source

DISTENDER indicators for Round2a (climate and socioeconomic signal) and for: Air Quality and Emissions; Urban Heat Island; Health; Water; Energy; Agroforestry; Sectorial economy; Risk and Vulnerability. Case study: Austria. Global climate model: Ind. Scenario: SSP245.

DISTENDER, ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON UOA, UNIVERSIDADE DE AVEIRO, UNIVERSITAT ZU KOLN, CLIMATE SOLUTIONS UNIPESSOAL LDA, UNIVERSIDAD POLITECNICA DE MADRID, UK CENTRE FOR ECOLOGY & HYDROLOGY   +6 more
openalex   +1 more source

TTNPB Promotes Human Pluripotent Stem Cell‐to‐Neural Stem Cell Transition via Modulation of Chromatin Accessibility and the S‐(5′‐adenosyl)‐L‐homocysteine/Choline Metabolic Network

Advanced Science, EarlyView.
A retinoic acid receptor agonist, TTNPB, drives the efficient generation of advanced neural stem cells (ANSCs) from human pluripotent stem cells. TTNPB‐centered chromatin remodeling and metabolic reprogramming, promote neuroectoderm commitment. The resulting cells show robust neural potential and functional efficacy in a rat depression model.
Ruilin Du, Yudi Ren, Qiaoqiao Meng, Peng Wei, Ruyu Zhu, Junjie Bao, Ye Yang, Shuo Yan, Chaorong Yue, Xueying Zhu, Shuo Cao, Chunxia Hao, Wei Sun, Yongli Song, Xihe Li, Zhimin Wu, Siqin Bao, Yanglin Chen   +17 more
wiley   +1 more source

Global climate change and seasonal variation of cellulitis in hospitalized children: a 30 year retrospective study. [PDF]

Epidemiol Infect
Megged O, Raphael A, Burstyn A, Deri N, Schwartz S, Eisenberg R, Toker O.   +6 more
europepmc   +1 more source

DISTENDER indicators for Round2a (climate and socioeconomic signal) and for: Air Quality and Emissions; Urban Heat Island; Health; Water; Energy; Agroforestry; Sectorial economy; Risk and Vulnerability. Case study: Austria. Global climate model: MPI-ESM1-2-HR. Scenario: SSP585.

DISTENDER, ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON UOA, UNIVERSIDADE DE AVEIRO, UNIVERSITAT ZU KOLN, CLIMATE SOLUTIONS UNIPESSOAL LDA, UNIVERSIDAD POLITECNICA DE MADRID, UK CENTRE FOR ECOLOGY & HYDROLOGY   +6 more
openalex   +1 more source

SR‐B1‐Mediated Transplacental Transfer of Hydrophobic Toxicants Disrupts Fetal Development During Barriergenesis

Advanced Science, EarlyView.
This study maps the spatiotemporal distribution of hydrophobic toxicants and endogenous metabolites in the developing placenta and fetus. By integrating mass spectrometry imaging with snRNA‐seq, we identify SR‐B1 as a key transporter driving early‐gestation xenobiotic transfer and reveal a critical exposure window associated with persistent fetal ...
Yixuan Huang, Hailin Shang, Ling Jiao, Ce Chen, Zehua Liu, Yi Yang, Qiannan Zhang, Song Tang, Xudong Jia, Hui Yang, Yi Wan   +10 more
wiley   +1 more source

Land system changes of terrestrial tipping elements on Earth under global climate pledges: 2000-2100. [PDF]

Sci Data
Lv J, Gao Y, Song C, Chen L, Ye S, Gao P.   +5 more
europepmc   +1 more source

Ultrasound Modulation of Visual Circuits in Mice Independent of Auditory Confound

Advanced Science, EarlyView.
In this study, Qiu et al. found that low‐intensity ultrasound can directly activate sparse ultrasound‐sensitive neurons (UNs) in the primary visual cortex (V1) of deafened mice. The proportion of these sparse UNs is pressure‐dependent. Furthermore, ultrasound modulates visual circuitry with distinct excitatory and inhibitory effects.
Jiaru He, Jiejun Zhu, Xinxin Wang, Zihao Chen, Jin Yang, Zhen Yuan, Hongzhi Xu, Lei Sun, Zhihai Qiu   +8 more
wiley   +1 more source