Results 81 to 90 of about 2,243,884 (354)
Pledging, Populism, and the Paris Agreement: The Paradox of a Management-Based Approach to Global Governance [PDF]
, 2019 For many observers, the Paris Agreement signaled a historic breakthrough in addressing the problem of global warming. In its basic design, however, the Agreement is far from novel.
Coglianese, Cary
core +2 more sources
A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling +16 more
wiley +1 more source
Scenarios and roots of climate change [PDF]
, 2012 There have been more and more words about climate change and global warming in the last few decades. But what do we really understand them? Is it logic that the climate change derived by human behaviour or is it an independent process of nature that ...
Hegedűs, Krisztina
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Arthritis Care &Research, EarlyView.Objective Antinuclear antibodies (ANAs) are present at high titers in 2% of the general population, but their clinical significance in individuals without an autoimmune (AI) disease is not known. We tested the hypothesis that the presence of a high ANA titer in non‐AI conditions is associated with disease.
Matthew Chung +7 more
wiley +1 more source
On estimating local long-term climate trends [PDF]
, 1992 Climate sensitivity is commonly taken to refer to the equilibrium change in the annual mean global surface temperature following a doubling of the atmospheric carbon dioxide concentration.
Chapman, Sandra C. +2 more
core +3 more sources
Arthritis Care &Research, EarlyView.Objective This study aimed to characterize the pharmacokinetics, pharmacodynamics, safety, and exploratory efficacy of subcutaneous belimumab in pediatric patients with active systemic lupus erythematosus (SLE) receiving standard therapy. Methods This single‐arm, multicenter, open‐label trial (GSK study 200908; ClinicalTrials.gov identifier ...
Hermine I. Brunner +14 more
wiley +1 more source
Addressing Economic Insecurities Can Improve Patient‐Reported Outcomes in Lupus
Arthritis Care &Research, Accepted Article.Background Economic insecurities, such as food, housing, transportation, and financial challenges, are modifiable risk factors and influence patient‐reported outcomes (PROs) in systemic lupus erythematosus (SLE). We examined: 1) associations between economic insecurities and PROs; 2) the impact of screening and addressing economic insecurities during ...
Jay Patel +8 more
wiley +1 more source
Climatic system as constituent of naturally- resource potential of economy [PDF]
, 2007 Social and ecological and economic consequences and damage, related to the change of climate require making of taking measures on adaptation to these changes and softening of their consequences, that will allow economic to ground made decisions on the ...
Telepenko, Irina
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Innovating Aircraft Repair Processes: The Role of Digitalization in Sustainability
Advanced Engineering Materials, EarlyView.This research explores how digitalization—by storing detailed non‐destructive testing data in structured DICONDE databases and creating a standard data model of the component—innovates aviation maintenance and repair processes. Coupled with a developed state‐based simulation model, it enables data‐driven, sustainable repair strategies that reduce waste,
Johanna Aigner +3 more
wiley +1 more source
Global Climate Action – May Update: [PDF]
The Climate Institute\u27s May update on the most recent developmentson new targets and other policies. Overview In the lead-up to the Paris climate talks in November, countries are advancing their domestic climate and clean energy efforts and ...
Climate Institute
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