Results 101 to 110 of about 2,061,932 (305)
Inverted Commons: Africa’s Nature in the Global Imagination. [PDF]
, 2012 Nature in Africa has long occupied a special place in the global imagination: the prevailing images associated with the continent are of a “wild Eden,” of rugged, “pristine” landscapes, and of some of the world’s most charismatic “megafauna” (elephants ...
Büscher, B.E. (Bram)
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Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Spatially contextualized analysis of energy use for commuting in India
Environmental Research Letters, 2019 India’s land transport GHG emissions are small in international comparison, but growing exponentially. Understanding of geographically-specific determinants of GHG emissions is crucial to devise low-carbon sustainable development strategies.
Sohail Ahmad, Felix Creutzig
doaj +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
OER and open licenses: the dual-pub solution [PDF]
, 2011 OER are teaching, learning, and research resources that reside in the public domain or have been released under an intellectual property license that permits their free use or re-purposing by others.
Ahrash N. Bissell
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CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Global Commons im 20. Jahrhundert
, 2014 With its international perspective and by situating itself “beyond the market and state,” this volume promises to generate many new insights for readers. Space and territorialization, global integration and statehood, law and international organizations – these dimensions of the global commons enrich our perspectives on the Cold War, decolonization ...
Löhr, Isabella, Rehling, Andrea
openaire +3 more sources
Measuring the configurational temperature of a binary disc packing
, 2014 Jammed packings of granular materials differ from systems normally described by statistical mechanics in that they are athermal. In recent years a statistical mechanics of static granular media has emerged where the thermodynamic temperature is replaced ...
Schröter, Matthias, Zhao, Song-Chuan
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Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Book review: the sustainable economics of Elinor Ostrom: commons, contestation and craft by Derek Wall [PDF]
, 2015 The threat posed by global warming and environmental degradation are the most pressing examples of what has become known over the past several decades as the ‘tragedy of the commons’. In this book, Derek Wall explores the work of the late Nobel Laureate,
Shaw, Christopher
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