Results 111 to 120 of about 2,103,834 (306)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Features of post-crisis protectionism in Asia and the Pacific [PDF]

open access: yes
This paper provides an overview of developments in implementation of protectionist measures relevant for Asia-Pacific economies in the period associated with recovery after the Global Economic Crisis of 2008/2009. At the very start of the Global Economic
Martin Wermelinger
core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

The Economic Crisis in Russia: Fragility and Robustness of Globalisation [PDF]

open access: yes
It is now clear that the global economic crisis has hit the Russian economy. The resulting shock clearly shows not only the global economic imbalance but also the distinct characteristics of emerging Russian markets.
Satoshi Mizobata
core  

Malaysian banking sector outlook during global financial crisis [PDF]

open access: yes, 2009
This paper is to discuss the Malaysian banking sector outlook and examine whether Malaysian banks are well placed to weather this Global Financial Crisis.
Tan, Lai Hock
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Beyond the Crisis: Financial Regulatory Reform in Emerging Asia [PDF]

open access: yes
The main objective of this paper is to suggest reform measures to address the gaps and weaknesses in emerging Asia's financial regulatory and supervisory systems, on the basis of lessons drawn from the global crisis.
Lee, Chee Sung, Park, Cyn-Young
core  

U.S. Retailers: Responsible for the Global Sweatshop Crisis [PDF]

open access: yes, 2001
This report provides an overview of the global sweatshop system, and offers a closer look at some of the more “prominent perpetrators” within the system, including: Ann Taylor, Abercrombie & Fitch, Eddie Bauer, Gap, Old Navy, Banana Republic, and J ...
Behind the Label (UNITE HERE)
core   +1 more source

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