Results 71 to 80 of about 183,036 (260)
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Formation and implementation of the strategic guidelines of anti-crisis development of the international consulting companies [PDF]
International Economic Policy, 2011 Baesd on the analisis of theoretical approaches to strategic changes of the company’s behavior, forecasting scenarios and forms of global financial crisis development, comparative features of diagnostics of the types of management system and its problems,
Larysa Rudenko-Sudarieva +1 more
doaj
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Impact of Crisis on Logistics Management [PDF]
Revista de Management Comparat International, 2010 Is the current situation facing the whole world and we need to adapt to withstand a fierce weather. Because the supply, which can be seen both as a sale (the manufacturers buy from suppliers) as well as a purchase (customers are supplied by producers) is
Daniel Constantin JIROVEANU +1 more
doaj
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
The effect of labour migration and structural changes on economic development
Вісник Харківського національного університету імені В.Н. Каразіна: Серія ЕкономікаThe article aims to analyze effects of the labour migration and structural changes on economic development. The Russian invasion in Ukraine increased geopolitical risks for the global economy in 2022 and in the present time.
O. Nosova
doaj +1 more source
Managing the Crisis in Iceland and the Dishonesty of the International Community? [PDF]
Revista de Management Comparat International, 2014 The 2008 global crisis hit hard in Iceland. During the crisis its three largest banks all collapsed in just a few days. This article focuses on the actions of the international community when the Icelandic authorities, during a period of great need and ...
Hilmar Þór HILMARSSON
doaj
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Shifting drug markets in North America - a global crisis in the making? [PDF]
Int J Ment Health Syst, 2023 Meyer M +9 more
europepmc +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source