Results 71 to 80 of about 6,256,309 (232)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

HOW CLOSE ISLAMIC BANKS ARE TO GLOBAL FRAUD- LEARNINGS FROM DUBAI ISLAMIC BANK IN THE TIME OF SUB-PRIME CRISIS

open access: yesEuropean Journal of Islamic Finance, 2018
This paper attempts to reconstruct and achieve learning from the mega financial crime that occurred at Dubai Islamic Bank (DIB) during the global crisis and juxtapose it with fraudulent practices from a global perspective with the aim to acquire a ...
Khairul Mukminin
doaj   +1 more source

Financial Crisis Inquiry Commission

open access: yes, 2011
This website contains the research and final report for the Financial Crisis Inquiry Commission looking at the causes of the economic ...
United States. Financial Crisis Inquiry Commission.
core  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

IMPORTANCE OF COMMUNICATION IN ORGANIZATIONAL INTELLIGENCE DEVELOPMENT IN THE CONTEXT OF GLOBAL CRISIS [PDF]

open access: yesChallenges of the Knowledge Society, 2012
It is now clear that different ways to generate, integrate and apply knowledge within organizations varies accordingly, at least, with the human factor, regardless privileged modalities of interactions between the firm and the environment. In the current
MANOELA POPESCU
doaj  

East Asia and the global/transatlantic/Western crisis [PDF]

open access: yes, 2011
This paper introduces the special collection on East Asia and the Global Crisis. After justifying why a focus on East Asia is appropriate, it draws out the main themes that run through the individual contributions.
Breslin, Shaun, Shaun Breslin
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

La ecología política de la crisis global y los límites del capitalismo benévolo [PDF]

open access: yesÍconos, 2010
Si bien la actual crisis global cambia el balance e intensidad de la presión ambiental en los ecosistemas de América del Sur, persisten las estrategias de desarrollo, bajo una intensa apropiación de los recursos naturales, una inserción primarizada en el
Eduardo Gudynas
doaj  

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