Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
GLOBALIZATION AND GLOBAL SOFTWARE DEVELOPMENT
Issues In Information Systems, 2007 openaire +3 more sources
GLocal: A global development dataset of subnational administrative areas. [PDF]
Sci DataMorales-Arilla J, Gadgin Matha S.
europepmc +1 more source
An outlook on the global development of renewable and sustainable energy at the time of COVID-19. [PDF]
Energy Res Soc Sci, 2020 Hosseini SE.
europepmc +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Next-Generation CAR-T and TCR-T Cell Therapies for Solid Tumors: Innovations, Challenges, and Global Development Trends. [PDF]
Cancers (Basel)Sanomachi T +3 more
europepmc +1 more source
Genome Edited Crops Touch the Market: A View on the Global Development and Regulatory Environment. [PDF]
Front Plant Sci, 2020 Menz J +4 more
europepmc +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Global development assistance for early childhood care and education in 134 low- and middle-income countries, 2007-2021. [PDF]
BMJ Glob HealthLuan Y +6 more
europepmc +1 more source
Not one, but many "publics": public engagement with global development in France, Germany, Great Britain, and the United States. [PDF]
Dev Pract, 2020 Hudson J +4 more
europepmc +1 more source