Results 71 to 80 of about 8,296,108 (395)
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Initial boundary value problem for a class of p-Laplacian equations with logarithmic nonlinearity
Mathematical Biosciences and Engineering, 2021 In this paper, we discuss global existence, boundness, blow-up and extinction properties of solutions for the Dirichlet boundary value problem of the $ p $-Laplacian equations with logarithmic nonlinearity $ u_{t}-{\rm{div}}(|\nabla u|^{p-2}\nabla u ...
Fugeng Zeng, Yao Huang , Peng Shi
doaj +1 more source
Global existence for a go-or-grow multiscale model for tumor invasion with therapy
, 2016 We investigate a PDE–ODE system describing cancer cell invasion in a tissue network. The model is an extension of the multiscale setting in [G. Meral, C. Stinner and C.
Christian Stinner +2 more
semanticscholar +1 more source
Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms
FEBS Letters, EarlyView.Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze +3 more
wiley +1 more source
Global existence for the Euler-Maxwell system [PDF]
Annales scientifiques de l'École normale supérieure, 2014 33 ...
Pierre Germain, Nader Masmoudi
openaire +3 more sources
Local and Global Existence of Solution for Love Type Waves with Past History
Mathematics, 2020 In this paper, we consider an initial boundary value problem for nonlinear Love equation with infinite memory. By combining the linearization method, the Faedo–Galerkin method, and the weak compactness method, the local existence and uniqueness of weak ...
Mohamed Biomy +2 more
doaj +1 more source
Global Existence of Classical Solutions for A Class Nonlinear Parabolic Equations [PDF]
, 2016 In this article we prove the existence of classical solutions for a class nonlinear parabolic equations. We propose new integral representation of the classical solutions.
Georgiev, S. G. (Svetlin)
core
Global existence for a degenerate haptotaxis model of cancer invasion [PDF]
, 2015 We propose and study a strongly coupled PDE–ODE system with tissue-dependent degenerate diffusion and haptotaxis that can serve as a model prototype for cancer cell invasion through the extracellular matrix.
A. Zhigun, C. Surulescu, Aydar Uatay
semanticscholar +1 more source
FEBS Letters, EarlyView.Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma +8 more
wiley +1 more source
Existe realmente o aquecimento global?
Research, Society and Development, 2022 A influência da temperatura nos organismos é um dos aspectos essenciais para a regulação e manutenção da vida. Ao longo do tempo geológico a temperatura na Terra oscilou entre extremos, como consequência de fenômenos geológicos naturais. Porém, especialmente a partir do século XX, algumas atividades antrópicas estão alterando o clima, ocasionando ...
Roberto Valmorbida de Aguiar +3 more
openaire +2 more sources