Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
Paradigm Shift in Global Governance of Medical Brain-Computer Interface: Addressing Practical Challenges Through Institutional Innovation. [PDF]
Zhu R, Zhao Y, Li Y.
europepmc +1 more source
Governing antimicrobial resistance: a narrative review of global governance mechanisms. [PDF]
Ruckert A +10 more
europepmc +1 more source
WHO simulations for youth engagement in global governance in a post-COVID world: Opportunities and challenges of moving conferences online. [PDF]
Li J +9 more
europepmc +1 more source
All Politics Is Global: Explaining International Regulatory Regimes [PDF]
Has globalization diluted the power of national governments to regulate their own economies? Are international governmental and nongovernmental organizations weakening the hold of nation-states on global regulatory agendas? Many observers think so.
Daniel W. Drezner
core
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
A "True Lifecycle Approach" towards governing healthcare AI with the GCC as a global governance model. [PDF]
Solaiman B +5 more
europepmc +1 more source
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin +12 more
wiley +1 more source

