Results 51 to 60 of about 5,779,825 (391)
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Deliberators, not Future Citizens: Children in Democracy
Journal of Deliberative Democracy, 2017 This paper is a “manifesto” for incorporating children into deliberative democracy. Although the United Nations Convention on the Rights of the Child (1989) emphasizes children’s right to participation in the process of democracy, their activities and ...
Kei Nishiyama
doaj +2 more sources
The Datafication of #MeToo: Whiteness, Racial Capitalism, and Anti-Violence Technologies
Big Data & Society, 2021 This article illustrates how racial capitalism can enhance understandings of data, capital, and inequality through an in-depth study of digital platforms used for intervening in gender-based violence.
Kathryn Henne, Renee Shelby, Jenna Harb
doaj +1 more source
Institutional consequentialism and global governance [PDF]
, 2017 Elsewhere we have responded to the so-called demandingness objection to consequentialism – that consequentialism is excessively demanding and is therefore unacceptable as a moral theory – by introducing the theoretical position we call institutional ...
Miklós, András, Tanyi, Attila
core +2 more sources
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Putting Global Governance in its Place
The World Bank Research Observer, 2019 Greater interdependence is often taken to require more global governance, but the logic requires scrutiny. Cross-border spillovers do not always call for international rules.
D. Rodrik
semanticscholar +1 more source
FEBS Letters, EarlyView.Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke +2 more
wiley +1 more source
Administrative SciencesInternational activities by all NGOs have become ubiquitous. Therefore, international non-governmental organizations (INGOs) are significantly and gradually increasing their international influence shaping a new paradigm for global affairs ranging from ...
Xue Zhang, Raafat George Saadé
doaj +1 more source
Dispute Settlement for Labour Provisions in EU Free Trade Agreements: Rethinking Current Approaches
Politics and Governance, 2017 While labour provisions have been inserted in a number of EU free trade agreements (FTAs), extant clauses are widely perceived as ineffective. This article argues that there is a need to rethink the dispute settlement mechanisms related to labour ...
Axel Marx, Franz Ebert, Nicolas Hachez
doaj +1 more source