Results 141 to 150 of about 5,735,852 (363)

No time for complacency on the road to gender equality

open access: yesThe Lancet Global Health, 2020
The Lancet Global Health
doaj   +1 more source

Global Trade Impacts: Addressing the Health, Social and Environmental Consequences of Moving International Freight Through Our Communities [PDF]

open access: yes, 2011
Examines freight transportation industry trends; the impact of global trade on workers, the environment, and health in both exporting and importing countries; and organizing strategies and policy innovations for minimizing the damage and ensuring ...
Andrea Hricko   +3 more
core  

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

End-stage kidney disease in LMICs: rising to the challenge

open access: yesThe Lancet Global Health, 2017
The Lancet Global Health
doaj   +1 more source

Now and then: lessons from the rollout of ART

open access: yesThe Lancet Global Health, 2021
The Lancet Global Health
doaj   +1 more source

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