Results 41 to 50 of about 2,414,043 (266)
CDC's Global Health Agenda [PDF]
Presentation at the Global Health Community meeting, June 3, 2016.Publication date from document properties.GHC-DC-Meeting_June-3_Martin ...
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Division of Global Health Protection (DGHP) [PDF]
Protecting the health and safety of Americans and people around the world 24/7To ensure global health security, every country needs a robust public health system that can rapidly respond to emergencies.
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
CDC global health strategy (2012-2015) : 2012 annual progress report [PDF]
The vision of CDC\u2019s global heath strategy is a world where people live healthier, safer, and longer lives through science, policy, partnership, and evidence-based public health action.
core
Access to and quality of elective care: a prospective cohort study using hernia surgery as a tracer condition in 83 countries [PDF]
background: timely and safe elective health care facilitates return to normal activities for patients and prevents emergency admissions. surgery is a cornerstone of elective care and relies on complex pathways.
Sica Giuseppe +1 more
core +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
CDC Center for Global Health (CGH) 2016 annual report [PDF]
CGH coordinates global health activities across CDC. CGH is made up of four divisions: Division of Global Health Protection (DGHP), Division of Global HIV & TB (DGHT), Division of Parasitic Diseases and Malaria (DPDM), and Global Immunization Division ...
core
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source